Chapter 11 - Efferent Division: Autonomic and Somatic Motor Control Flashcards
the maintenance of homeostasis within the body is a balance of:
autonomic control, endocrine control, and behavioral responses
the autonomic division is controlled by:
centers in the hypothalamus, pons, and medulla
all preganglionic neurons secrete ___ onto ___ receptors
ACh, nicotinic cholinergic receptors
postganglionic sympathetic neurons secrete ___ onto ___ receptors
NE, adrenergic receptors
postganglionic parasympathetic neurons secrete ___ onto ___ receptors
ACh, muscarinic cholinergic receptors
NE release and removal at a sympathetic neuroeffector junction
- action potential arrives at the varicosity. 2. depolarization opens voltage-gated Ca2+ channels. 3. Ca2+ entry triggers exocytosis of synaptic vesicles. 4. NE binds to adrenergic receptor on target. 5. receptor activation ceases when NE diffuses away from the synapse. 6. NE is removed from the synapse. 7. NE can be taken back into synaptic vesicles for re-release. 8. NE is metabolized by monoamine oxidase (MAO)
the main enzyme for catecholamine metabolism/degradation
monoamine oxidase (MAO)
postganglionic autonomic axons end w/ ___ from which neurotransmitter is released
varicosities
the adrenal medulla secretes:
epinephrine primarily. (medulla is a/w sympathetic branch)
adrenergic receptors are:
G protein-coupled receptors
enzyme that breaks down ACh
acetylcholinesterase
alpha (1 and 2) adrenergic receptors respond most strongly to:
NE
beta1 adrenergic receptors respond:
equally to NE and E
beta2 adrenergic receptors respond most strongly to:
E (and are not a/w sympathetic neurons)
beta3 adrenergic receptors respond most strongly to:
NE