Chapter 14 & 15: Developmental and Childhood Disorders Flashcards
What are neurodevelopmental disorders?
- disorders that begin generally before, during, or soon after birth, though they may not be detected for some time depending on severity
What are disorders of childhood and adolescence?
- emergent as a child develops, perhaps more due to environment than a gestational disorder
What is intellectual disability?
- refers to significantly subaverage intellectual functioning beginning before the age of 18, and accompanied by limitations in two or more areas of adaptive skill
What is autism?
- best known of the neurodevelopmental disorders
- characterized by a lack of responsiveness, unusual responses to the environment, and absent or unusual expressive language
What are the DSM-V changes concerning developmental disorders?
- “mental retardation” replaced with “intellectual disability”
- more emphasis placed on cultural issues and adaptive functioning
- manifested in several diagnostic categories:
→unusual physical features,
→ deficits in language,
→ motor ability, and other skills,
→ and patterns of behaviour such as hyperactivity, aggressiveness, or stereotypy (the repetition of meaningless gestures or movements)
What is the prevelance of intellectual disability in Canada?
- 8 per 1000 in general
- children aged 7-10 is ~3.65 per 1000
What are the diagnostic issues for intellectual disability?
- level of IQ
→ may have average/high IQ but deficits in adaptive behaviour - American Association on Mental Retardation (AAMR) has strongly influenced definition and classification of “intellectual disabiliity”
→ *
How is adaptive behaviour measured?
- Vineland Adaptive Behaviour Scales
→ completed during interviews with parents, teachers, or caregivers - Scales of Independent Behaviour
→ evaluates level of support needed in each domanin of functioning - Adaptive Behaviour Assessment System
→ norms for adaptive behaviour and related skills from 5-89 years of age
What are the genetic causes of developmental disorders?
- dominant inheritance
→ rare, but seen in tuberous sclerosis and neurofibromatosis - recessive inheritance
→ phenylketonuria, Tay-Sachs disease, galactosemia - sex-linked
→ Fragile X syndrome, Lesch-Nyah syndrome
What is an example of chromosomal abnormalities in developmental disorders?
- Down Syndrome
→ extra chromosome on pair 21 (Trisomy 21)
→ translocation
→ mosaicism
*
What is amniocentesis?
*
What is chorionic villus sampling (CVS)?
*
What is phenylketonuriea (PKU)?
- best known of several rare metabolic disorders that can cause Intellectual Disability
How is PKU treated?
- dietary treatment beginning early in infancy typically results in intellectual functioning within the normal range
What are examples of other metabolic disorders?
→ congenital hypothyroidism
→ hyperammonemia
→ Gaucher’s disease
→ Hurler’s syndrome
What is congenital hypothyroidism?
*
What is hyperammonemia?
*
What is Gaucher’s disease?
*
What is Hurler’s syndrome?
*
What are environmental causes of developmental disorders?
- fetus exposed to toxins (e.g., drugs or alcohol) or infections (e.g., rubella or HIV)
- blood supply lacks nutrients or oxygen
- birth-related trauma, though rare
What is the psychosocial disadvantage model of intellectual disability?
- psychological and social deprivation, due to lack of stimulation and care
- poverty, poor nutrition, large family size, lack of structure in the home, and low academic expectations
- approx. 75% of people diagnosed as having a neurodevelopmental disorder, no organic cause or brain dysfunction has been identified
What studies support genetic effects of developmental disorders?
- he IQ scores of monozygotic twins are significantly more concordant than those of dizygotic twins
- adoption studies suggest that intelligence scores are affected more by the genetic makeup of the biological parents and possibly prenatal environmental factors than by environmental input provided by adoptive parents.
What are early intervention methods that can reduce developmental disorder symptoms?
- encouragement of exploration
- assistance in basic skills
- guided rehearsal and extension of new skills
- protection from inappropriate disapproval, teasing, or punishment
- rich and responsive language environment
- supportive and predictable environment in terms of opportunities for learning and patterns of interaction
What is Fragile X syndrome?
- characterized by a weakened or “fragile” site on the X chromosome
- second most frequently occurring chromosomal abnormality causing intellectual disability
→ most common hereditary cause
What are the common symptoms of Fragile X syndrome?
*
What does social inclusion strategy for developmental disorders entail?
- active process that can enhance participation and development of individuals with neurodevelopmental disorders
- preparation for community living
→ educational programs for people with neurodevelopmental disorders have focused on developing social skills and independent living skills
→ reducing or managing maladaptive behaviours
What is the normalization principle?
- lives of individuals with disabilities should be as normal as possible
- contributed to the deinstitutionalization of thousands of people with disabilities and the provision of community-based accommodation and services
What is dual diagnosis?
- co-occurrence of serious behavioural or psychiatric disorders (like emotional and behavioural problems) in people with neurodevelopmental disorders
How is dual diagnosis treated?
- behavioural approach
→ intervention of choice for maladaptive behaviours such as aggression, destructiveness, and self-injury
Who is Leo Kanner?
- identified autism as a childhood disorderr in 1943
What is the prevalence of autism spectrum disorder in Canada?
- 1 to 3 per 1000 births
- higher IQ variant occurs three times more often in men than women
What are the two features of autism spectrum disorder?
- social dysfunction
- unusual responses to the environment