Chapter 13: Med Surg Flashcards
regeneration
replacement of lost cells and tissues with cells of the same type
repair
healing as a result of lost cells being replaced by connective tissue
epithelial regenerative ability
skin, blood vessels, mucous membrane; readily regenerate
connective tissue regenerative ability
bone active tissue regenerates, cartilage regeneration possible but slow, tendons and ligaments regeneration possible but slow, blood cells actively regenerate
muscle regenerative ability
smooth regeneration possible mostly in GI tract, cardiac muscle is replaced by connective tissue, skeletal muscle some regeneration in moderately damaged muscle, but mostly connective tissue replaces severely damaged
nerve regenerative ability
neuronal is nonmitotic aka irreversibly damaged, glial the cells regenerate and scar tissue replaces
what type of cells regenerate constantly?
labile cells (skin, lymphoid, bone marrow, and mucous membranes)
what type of cells only regenerate if damaged?
stable cells (liver, pancreas, kidney, bone cells)
what type of cells do not regenerate?
CNS and skeletal and cells muscle
primary intention
healing takes place where wound margins are neatly approximated (e.g. surgical incision or paper cut)
initial phase
lasts for 3-5 days, incision fills with blood to form clots and begin healing process, macrophages ingest and digest debris and fragments to begin capillary growth
granulation phase
5 days-4 weeks, fibroblasts migrate, secrete collagen, the wound is pink, vascular, and red granules are present, wound begins to resemble adjacent skin
maturation phase and scar contraction
7 days to several months, overlaps granulation phase, fibroblasts disappear as the wound becomes stronger, myofibroblasts help to cause contraction and close the wound, may be painful
secondary intention
wounds that occur from trauma, ulceration, and infection have large amounts of exudate and wide irregular wound margins, healing and granulation take place from the edges inward and from the bottom upward and there is more granulation tissue, so the scar is bigger
tertiary intention
delayed primary healing, wound may be left open and sutured closed after the infection is controlled, resulting in a larger and deeper scar
what classifies a wound as chronic?
does not heal within 3 months
red wound
superficial or deep, clean and pink, possible serosanguineous
examples of red wounds
skin tears, stage 2 pressure ulcers, partial thickness loss, second degree burns, wounds that heal by secondary intention
red wound dressings
transparent dressing, hydrocolloid, gauze, gentle atraumatic cleansing permeable to oxygen
yellow wound
prescence of slough or soft necrotic tissue, creamy ivory to yellow-green
examples of yellow wounds
wounds with nonviable necrotic tissue
yellow wound dressings
absorptive dressing, hydrocolloidal dressing, hydrogel, wound irrigations, moist gauze, wound cleansing to remove nonviable tissue and absorb excess drainage, left in place for up to 7 days
black wound
black, gray, or brown, eschar, risk of wound infection high
examples of black wounds
full thickness loss, third degree burns, stage 3 and 4 pressure ulcers, gangrenous ulcers
black wound dressings
topical debridement, hydrogel, absorptive dressing, debridement of eschar and nonviable tissue
lack of Vitamin C effects the wound by
delays collagen production for fiber and capillary development
lack of protein effects the wound by
decreases amino acids for tissue repair
lack of zinc effects the wound by
impairs epithelialization
inadequate blood supply effects the wound by
decreases supply of nutrients to the effected area, decreases removal of nonviable tissue, inhibits inflammatory response necessary in the initial stage
corticosteroid drugs effect the wound by
impair phagocytosis of WBCs, inhibit fibroblasts, depress granulation tissue, and inhibit wound contraction necessary for the last stage of healing
infection effects the wound by
increases the inflammatory response too much and tissue destruction
smoking effects the wound by
impedes blood flow to healing area
obesity effects the wound by
decreasing blood supply in fatty tissue
diabetes effects the wound by
decreasing collagen synthesis, retards capillary growth, impairs phagocytosis (resulting from hyperglycemia), reduces supply of O2
anemia effects the wound by
supplies less oxygen at tissue level