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MICROBIO > Chapter 13 > Flashcards

Chapter 13 Flashcards

1
Q

What do viruses contain ?

A

DNA or RNA

protein coat

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2
Q

Host range

A

spectrum of hots a virus can infect

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3
Q

viruses made up of what

A

nucleic acids

capsid

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4
Q

Nucleic acid

A

either DNA or RNA

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5
Q

Capsid

A

protein coat, 1+ type of proteins

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6
Q

Envelope

A

lipids, proteins and carbs

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7
Q

Spikes

A

carbohydrate proteins complexes

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8
Q

Three morphology

A

Helical
Polyhedral
Complex

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9
Q

Helical

A

long rod, rigid or flexible

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10
Q

Polyhedral

A

many sides, capsid

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11
Q

Complex

A

complex structures, bacteriophages

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12
Q

Living Animals

A

study immune response, diagnostic from clinical specimen

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13
Q

Embryonate eggs

A

virus injected into hole of egg

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14
Q

Cell cultures

A

grown in lab cell clutures

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15
Q

Replication Cycle

A

Attachment, penetration, biosynthesis, maturation, release

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16
Q

Lytic cycle

A

host cell dies; viruses produced in host cell, host cell lyses to release viruses

17
Q

Lysogenic cycle

A

hot cell survives; viral DNA integrates into host chromosome

18
Q

Attachment

A

tail fibers, bacteria receptors

19
Q

Penetration

A

tail core enters cell wall, viral DNA passes through

20
Q

Biosynthesis

A

host DNA degraded, uses host machinery to make copies of phage DNA

21
Q

Maturation

A

phage assemble

22
Q

Release

A

plasma membrane breaks, cell wall broken by lysozyme, new phages are released from host

23
Q

Multiplication

A

Attachment, entry, uncaring, biosynthesis, maturation, release

24
Q

Attachement

A

attachment sites on virus
virus attaches to host cell at numerous sites
receptors on host, genetic difference between individuals

25
Q

Entry

A

Receptors mediated endocytosis

Fusion- viral envelope fuses with plasma membrane, release capsid into cell

26
Q

Uncoating

A

nucleic acid is separated from protein coat

lysosomal enzyme of host cell, degrade capsid

27
Q

Biosynthesis

A

must make more nucleic acid and capsid protein

need a template to make more nucleic acid and mRNA to make protein

28
Q

Maturation

A

assembly of capsid

envelope protein into plasma membrane of host cell

29
Q

Release

A

budding

noneveloped viruses- rupture of plasma membrane release viruses

30
Q

Tumor Suppressor genes

A

genes that control unregulated cell growth normally turned on to control cell growth

31
Q

Oncogenic Viruses

A

induce tumors 10% cancers are viruses related

genes within the virus lead to uncontrollable cell division or interfere with tumor suppressor genes or oncogenes

32
Q

Latent infection

A

virus remains integrated in the host genome in periodic outburst

33
Q

Persistent viral infection

A

effects of virus infection occurs gradually over time

34
Q

Acute infection

A

short term

MICROBIO (6 decks)

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