Chapter 13 Flashcards

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1
Q

Surfaces of our body that have normal flora? List 6

A
Skin
Conjunctiva
Nasal cavity and nasopharyngeal
Mouth and intestinal tract
Vagina
Urethra
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2
Q

What’s the process of how you become infected? List 7

A
Pathogenicity
Portals of entry
Attachment
Surviving host defenses
Causing disease
Process of infections and disease
Portals of exit
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3
Q

What factors weaken host defense and increase susceptibility to infection? List 7

A
  1. Old age and extreme youth
  2. Genetic defects and acquired defects in immunity
  3. Surgery and organ transplant
  4. Organic disease: cancer, liver malfunction, diabetes
  5. Chemotherapy/ immunosuppressive drugs
  6. Physical and mental stress
  7. Other infections
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4
Q

Portals of Entry? List 6

A
Skin
GI Tract
Respiratory tract
Urogenital
Placenta
Inoculum size
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5
Q

What steps must a pathogen take to successful? List 7

A
  1. maintain a reservoir (a place to live before and after infection.)
  2. Leave the reservoir and enter a host.
  3. Adhere to the surface of a host.
  4. Invade the body of the host.
  5. Evade the body’s defenses.
  6. Multiply within the body.
  7. Leave the body and return to its reservoir or enter a new host.
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6
Q

Incubatory Carrier is what?

A

Seemingly healthy people who are affected but do not develop symptoms.

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7
Q

Chronic Carriers

A

Have harbored pathogen for months or years

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8
Q

What is Horizontal transmission?

A

Human contact

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9
Q

What is vertical transmission?

A

Mother to infant

Across placenta or perinatal (before or after birth)

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10
Q

What is vehicles transmission?

A

Inanimate objects
Fomites
Not a reservoir

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11
Q

Vectors

A

Biological- transmitted by bite, defecation, infected with pathogen
Mechanical-not part of pathogens life cycle (fly touch poop and land on you sandwich)
Anthropod

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12
Q

Fecal- oral route? List 4

A
  1. Infected feces to mouth of new host
  2. Direct hand to hand
  3. Hand to mouth by VEHICLES such as water, food and formites
  4. Vectors (flies to food)
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13
Q

What’s is parenteral transmission?

A

Microorganisms are deposited directly into blood vessels or deep tissue

  • biological vector bites through skin
  • IV drug users share needles
  • deep wounds or puncture wounds allowing anaerobic pathogens to enter
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14
Q

What is resident biota?

A

Inhabit the body throughout life, can never be reduced

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15
Q

Transient biota

A

Inhabit our body under certain circumstances and can be removed by cleansing.

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16
Q

Opportunists

A

Bacteria that cause disease when the host defense are weakened, or normal flora is altered.

Cause disease in immune compromised host.
Gain access (injury) to sterile regions
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17
Q

What happens at 2 weeks of birth.

A

General colonization of normal flora.

18
Q

What happens at 6 months?

A

Bacteria colonize gum line.
Streptococci
Fusobacterium
Bactericides

19
Q

how do bacteria change in vagina?

A

The increase or decrease of lactobacilli.

20
Q

What is commensalism?

A

Healthy humans and their normal flora

21
Q

What is mutualism?

A

Usually neither survives without the other. Example: digestive bacteria

22
Q

Parasitism

A

Pathogenic bacteria. Some commensals could become pathogenic under the right circumstances (makes them opportunist)

23
Q

What is an structural defense?

A

Skin

24
Q

What is a mechanical defense?

A
Blinking
Mucocilliary
Talking
Swallowing 
Chewing
25
Q

What is a biochemical defense?

A

Salt in sweat
Stomach acid
Tears
Saliva- lysozyme

26
Q

Name 3 basic defenses?

A

Structural
Mechanical
Biochemical

27
Q

What are bacteriocins?

A

Defensive toxins that inhibit competition

28
Q

What is a true pathogen

A

Cause cease in healthy individual. Specific and recognizable disease
Flu

29
Q

List 4 microbial environment of the Skin.

A
  1. Very dry
  2. Fatty acids can be inhibitory
  3. Lysozyme in sweat
  4. Salt can be inhibitory
30
Q

How does normal biota keep the skin healthy?

A

By occupying space

31
Q

What type of bacteria is found on the skin?

A

Staphylococcus
Diptheroids
Fungi
Mites

32
Q

Where are Diphtheroids found on body?

A

Sebaceous Glands

Live deep in hair follicles, feed on sebum

33
Q

Bacteroides come from where?

A

Gram negative, bacillus bacteria

They are non-endospore forming, anaerobes

34
Q

What causes most wound/procedure site infections.

A

Staph. Epidermidis

35
Q

Where is the first place to be colonized on human body?

A

The mouth

36
Q

Why is the mouth a violent place for bacteria?

A

Talkin
Chewing
Swallowing
Dislodge bacteria

37
Q

What is lysozyme?

A

Biochemical that constantly washes out the mouth

38
Q

How many different species in the normal flora?

A

80

39
Q

What causes tooth decay

A

Mutans

40
Q

What kind of bacteria is yeast and thrush?

A

Candida albicans

41
Q

How much bacteria is in feces

A

1/3 dry weight of feces