Chapter 13 Flashcards

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1
Q
Viruses possess genetic material comprised of DNA or \_\_\_\_\_\_\_\_\_\_.

  
NADPH
  
plasmids 
  
ATP 
  
guanine 
  
RNA
A

RNA

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2
Q
Which type of microscope is needed to view a virus in the laboratory? 

  
brightfield
  
electron 
  
compound 
  
fluorescent
  
darkfield
A

electron

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3
Q

Which of the following are possible strategies for treating viral infections?

blocking viral attachment to host cell receptors

blocking insertion of viral DNA into the host cell chromosomes

blocking uncoating of the virus after entry

blocking biosynthesis of viral nucleic acids

All of the listed strategies are correct.

A

All of the listed strategies are correct

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4
Q
A double-stranded, enveloped DNA virus that contains reverse transcriptase belongs to which family? 

  
Hepadnaviridae 
  
Rhabdoviridae 
  
Retroviridae 
  
Poxviridae 
  
Picornaviridae
A

Hepadnaviridae

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5
Q
Members of the Adenoviridae cause \_\_\_\_\_\_\_\_\_\_.

  
hepatitis 
  
smallpox
  
influenza
  
the common cold
  
cold sores
A

the common cold

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6
Q
Which method cannot be used to culture viruses in a laboratory? 

  
primates 
  
embryonated eggs 
  
tissue culture 
  
nutrient agar culture media 
  
live animals
A

nutrient agar culture media

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7
Q
Cell lines derived from transformed (cancerous) cells are called \_\_\_\_\_\_\_\_\_\_.

  
primary cell lines 
  
embryonated 
  
continuous cell lines 
  
plaques 
  
monolayers
A

continuous cell lines

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8
Q
During the bacteriophage lysogenic cycle, \_\_\_\_\_\_\_\_\_\_.

  
phage DNA is inserted into the host chromosome 
  
no attachment occurs 
  
new phage DNA is synthesized 
  
the burst time is shortened 
  
the host cell lyses, releasing new virions
A

phage DNA is inserted into the host chromosome

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9
Q
After the attachment and entry of a virus into a host cell, what is the next step in the multiplication of animal viruses? 

  
viral DNA is degraded by enzymes
  
uncoating 
  
synthesis of capsid proteins
  
transcription of "late" genes
  
transcription of "early" genes
A

uncoating

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10
Q
An example of a latent virus infection is \_\_\_\_\_\_\_\_\_\_.

  
smallpox 
  
influenza 
  
measles 
  
shingles 
  
polio
A

shingles

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11
Q
A virus may contain any of any of the following EXCEPT (a) \_\_\_\_\_\_\_\_\_\_. 

  
lipid envelope 
  
capsid proteins
  
ribosomes 
  
ssRNA 
  
spike proteins
A

ribosomes

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12
Q
Viruses that use RNA as a template for transcribing DNA include \_\_\_\_\_\_\_\_\_\_.

  
Rhabdoviridae 
  
Togaviridae 
  
Retroviridae 
  
Herpesviridae 
  
Picornaviridae
A

Retroviridae

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13
Q
All of the following are prion diseases EXCEPT \_\_\_\_\_\_\_\_\_\_.

  
Wiles-Davidoff syndrome 
  
Creutzfeldt-Jakob disease 
  
fatal familial insomnia 
  
Gerstmann-Straussler-Scheinker syndrome 
  
kuru
A

Wiles-Davidoff syndrome

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14
Q
Which of the following terms are NOT correctly matched? 

  
Poxviridae; chickenpox
  
Picornaviridae; polio 
  
Flaviviridae; hepatitis 
  
Herpesviridae; infectious mononucleosis 
  
Picornaviridae; common cold
A

Poxviridae; chickenpox

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15
Q

In polio virus replication, the function of the antisense (– strand) RNA is to __________.

allow a virus to enter the nucleus

serve as a template for the production of sense (+ strand) RNA

enhance the pathogenicity of the viral toxins

become incorporated into the capsid proteins

be translated for the production of capsid proteins

A

serve as a template for the production of sense (+ strand) RNA

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16
Q
How might a virus pick up a human oncogene?

  
reverse transcription
  
biosynthesis
  
specialized transduction 
  
transformation 
  
viral conversion
A

specialized transduction

17
Q
Influenza viruses are classified according to their hemagglutin and \_\_\_\_\_\_\_\_\_\_ proteins. 

  
nucleic 
  
neuraminidase 
  
arabinose 
  
amphiphilic 
  
polymorphic
A

neuraminidase

18
Q

To what does the term viral species refer?

viruses grouped according to their susceptibility to antibiotics

viruses grouped according to growth on selective media

a group of viruses that are reproductively isolated

a group of viruses sharing the same genetic information and structure

a group of viruses sharing the same disease symptoms

A

a group of viruses sharing the same genetic information and structure

19
Q
Which of these enzymes is necessary for the replication of a + strand RNA virus?

  
RNA-dependent RNA polymerase
  
DNA-dependent DNA polymerase
  
DNA-dependent RNA polymerase
  
RNA-dependent DNA polymerase
  
reverse transcriptase
A

RNA-dependent RNA polymerase

20
Q

Which of these statements is NOT true?

Penetration of enveloped viruses can occur by a process called fusion.

Uncoating can occur because of host cell lysosome action.

Attachment of animal viruses to host cells is random and nonspecific.

Animal viral DNA that is integrated into the host chromosome is called a provirus.

Enveloped viruses are released from the cell by budding.

A

Attachment of animal viruses to host cells is random and nonspecific.

21
Q

Viruses have a very high metabolic rate.

A

False

22
Q

Virus spikes are used for attachment to the host cell.

A

True

23
Q

During lysogeny, the phage remains latent

A

True

24
Q

The viral host range is largely dependent upon the attachment sites on the host cell.

A

False

25
Q

Poliovirus has a positive strand RNA that acts as the messenger RNA.

A

True

26
Q

During the maturation of enveloped animal viruses, some viruses acquire their envelope from the host cell membrane.

A

True

27
Q

Viruses range from 20 to 1000 nanometers in length and are easily seen using a compound light microscope.

A

False

28
Q

Oncolytic viruses can infect and destroy cells infected with cancer.

A

False

29
Q

Structurally, bacteriophages are complex viruses.

A

True

30
Q

Viruses can be grown only in living animal or plant hosts.

A

False