Chapter 13 Flashcards
Plasticity?
muscle fibers adapt to the habitual level of demand placed on them
Adaptation is a process of ________.
Remodeling
-form new mitochondria, more enzymes, more capillaries, more proteins
Remodeling occurs as long as ______.
training stimulus occurs
What makes the remodeling process more efficient?
when there is optimal nutrition and rest
T/F
All fiber types undergo some training adaptation.
True
Hypertrophy?
the CSA of muscle will enlarge due to an enlargement of the individual muscle fibers
What causes hypertrophy?
chronic exercise training, caused mainly by resistance training but is also affected by aerobic exercise
Myogenesis?
development of muscle tissue occurs during embyronic development, postnatal muscle growth, and as a mature adult
What cells play an important role in the growth of adult skeletal muscle resulting from physical training?
Myogenic precursor cells (satellite cells)
What activates satellite cells?
activated in response to muscle damage from injury, stretching, exercise
How do satellite cells repair muscle damage?
they donate their nuclei to the fibers, which helps them regenerate fiber, growth of CSA, not length
What fiber type has a greater number of satellite cells? why?
- ST
- b/c of their greater number of capillaries
- ST fibers have a broad range of activities, needed more for repair
How does the immune system respond the exercise?
Macrophages are attracted to the injured fiber, phagocytosis of debris, inflammation for repair and waste product removal
How does hormonal response contribute to hypertrophy?
- cortisol is released from adrenal cortex, stimulates the breakdown of proteins, increases the availability of amino acids for other functions
- growth hormone stimulates IGF which promotes satellite cell activation
- testosterone increases protein synthesis
The hypertrophy of skeletal muscle following exercise induced overload is a result of the combined effects of what?
immune, hormone, growth factor, satellite cells
What increases does hypertrophy cause?
- size of fibers
- number of myofibrils
- amount of actin, myosin
- cytoplasm
- capacity to exert force
Hyperplasia?
increase in CSA due to an increased number of fibers
What causes hyperplasia?
activated satellite cells fuse together forming new fibers instead of fusing with existing fibers (hypertrophy)