Chapter 12 - The Central Nervous System Flashcards
Embryonic Development
During the third week the ectoderm thickens forming what is known as a neural plate (dorsal midline axis of the embryo) this plate invaginate forming a groove that’s flanked with neural folds, as the neural groove deepens the edges fuse to form a neural tube, once it’s formed it detaches and it sinks to a deeper position
Embryonic Development: Neural Tube
- Formed by the 4th week of pregnancy, it differentiates into the CNS, there needs to be folic acid to close the neural tube
Embryonic Development: Primary Brain Vesicles
- Once neural tube forms its anterior end begins to expand forming the brain, the remainder of the neural tube becomes the spinal chord
a. Prosencephalon – aka forebrain → telencephalon and diencephalon
b. Mesencephalon – aka midbrain → mesencephalon
c. Rhombencephalon – aka hindbrain → metencephalon and myelencephalon
Embryonic Development: Secondary Brain Vesicles
- Appear in the 5th week from the PRIMARY BRAIN VESCILES
a. Telencephalon – aka end brain → cerebrum (cerebral hemispheres which are made up of the cortex, white matter and basal nuclei
b. Diencephalon – aka interbrain → thalamus, hypothalamus, epithalamis, and retina
c. Mesencephalon → mid brain of the brain stem
d. Metencephalon → pons
e. Myelencephalon → medulla oblongata
Embryonic Development: Flexures
- Midbrain and cervical – move the forebrain toward the brain stem and they’re formed because the brain grows faster than the skull
Embryonic Development: Adult Brain Structures
a. Cerebrum – two cerebral hemispheres come together
b. Diencephalon – thalamus, hypothalamus, epithalamis and retina
c. Midbrain – forms the brain stem along with other hindbrain structure
d. Pons – mesencephalon which also helps form the brain stem
e. Cerebellum – metenephalon helps form the brain stem
f. Medulla oblongata – myelencephalon and it helps form the brain stem
General Organization: Adult Brain Regions
a. Cerebral hemispheres
b. Diencephalon
c. Brain stem
d. Cerebellum
General Organization: Ventricles
Fluid filled and they’re continues enlargements that are formed by the central cavity of the neural tube, they’re continues with one another and the central canal of the spinal cord. CSF – cerebral spinal fluid and are lined by apendipal cells (neuroliga)
General Organization: Ventricles - Lateral
Paired found in cerebral hemispheres and they’re large C shaped chambers, anteriorly they lie close together and they’re separated by the septum pellucidum
i. Horns – anterior horn posterior horn and inferior horn
ii. Septum pellucidum – divides the lateral ventricles; thin median membrane that’s basically a transparent wall
General Organization: Ventricles - Third
Narrow found in the diencephalon that communicated with the lateral ventricles via interventicular foramen and the 4th ventricles
General Organization: Ventricles - Cerebral Aqueduct
Connects the 3rd and 4th ventricles; it is canal like
General Organization: Ventricles - Fourth Ventricle
Found in the hindbrain dorsal to the pons and superior to the medulla
i. Apertures – they connect the ventricles to subarachnoid space (fluid filled space found surround the brain); 2 types median and lateral
CNS Arrangement
a. Central cavity – hole in the middle
b. Inner gray matter core – area closest to the central cavity (butterfly shaped for spinal cord) mostly neuron cell bodies
c. Outer white matter – mostly mylinated fiber tracks (majority of CNS)
d. Gray matter nuclei – little circles within the outer white matter
e. Cortex of gray matter – only found in cerebellum which is basically the outer layer
Cerebral Hemispheres: Markings
a. Gyri – elevated ridges or tissue that’s found on the surface of the cerebral hemispheres
b. Sulci – shallow grooves
c. Fissures – deeper grooves
i. Longitudinal fissure – midline of the brain that separates the hemispheres
ii. Transverse cerebral fissure – separates the hemispheres from the cerebellum
Cerebral Hemispheres: Lobes
a. Frontal lobe
i. Central sulcus – divides the frontal and parietal lobes
ii. Precentral gyrus – anterior to the central sulcus
b. Parietal lobe
i. Postcentral gyrus – found posterior to the precentral gyrus
ii. Parieto-occipital sulcus – divides the parietal and occipital lobes
c. Occipital lobe – back of head
d. Temporal lobe – side of head
i. Lateral sulcus – divides that temporal and the parietal lobe
e. Insula – buried deep within the lateral sulcus and it forms part of its floor
Cerebral Hemispheres: Cerebral Cortex
Grey matter, neuron cell bodies, dendrites, associated gilia cells, but NO fiber tracks (aware of ourselves, sensations, communicate, remember, understand and innate voluntary movements)
Cerebral Hemispheres: Cerebral Cortex - Motor Areas (voluntary) - Primary Motor Cortex
A. Location – precentral gyrus of each hemisphere in the frontal lobe
B. Function – consciously control precise or skilled voluntary movement of our skeletal muscles
C. Pyramidal cells – large neurons found in the gyri that control movements
D. Somatotropy – mapping of the body in the CNS structures
Cerebral Hemispheres: Cerebral Cortex - Motor Areas (voluntary) - Premotor Cortex
A. Location – found anterior to the precentral gyrus or premotor cortext
B. Function – controls learned motor skills or a repetitious or patterned nature (typing); it coordinated region of several muscle groups
Cerebral Hemispheres: Cerebral Cortex - Motor Areas (voluntary) - Broca’s Area
A. Location – only in the left hemisphere, it’s found anterior to the inferior region of the premotor area
B. Function – directs muscles that are involved in speech production
Cerebral Hemispheres: Cerebral Cortex - Motor Areas (voluntary) - Frontal Eye Field
A. Location – partially in and anterior to the premotor cortext and superior to broca’s area
B. Function – controls voluntary movements
Cerebral Hemispheres: Cerebral Cortex - Sensory Areas - Primary Somatosensory Cortex
A. Location – in the post central gyri of the parietal lobe, posterior to the primary motor cortex
B. Function – receive information from the general sensory receptors in the skin and other receptors in skeletal muscles, joints and tendons
C. Somatotropy
Cerebral Hemispheres: Cerebral Cortex - Sensory Areas - Somatosensory Association Cortex
A. Location – posterior to the primary somatosensory cortex
B. Function – integrate sensory inputs (temperature and pressure) to produces an understanding of an object that is being felt
Cerebral Hemispheres: Cerebral Cortex - Sensory Areas - Primary Visual Cortex
A. Location – extreme posterior tip of the occipital lobe, most of it is buried deep within the sulcus and found in the medial part of the occipital lobe
B. Function – receives visual information that originates from the retina