Chapter 12: Lipids and Membranes Flashcards
Flippase
Aid in the movement of phospholipid molecules between the two leaflets that compose a cell’s membrane
Move lipids from the exoplasmic to the cytosolic face utilizing ATP
Floppase
Aid in the movement of phospholipid molecules between the two leaflets that compose a cell’s membrane
Move lipids from the cytosolic face to the exoplasmic utilizing ATP
Scramblase
Aid in the movement of phospholipid molecules between the two leaflets that compose a cell’s membrane WITHOUT the input of ATP
Bidirectional
Glycolipids
Carbohydrate-containing lipids derived from sphingosine
The carbohydrate is linked to the primary alcohol of sphingosine
Cholesterol
A steroid that is modified on one end by the attachment of a fatty acid chain and at the other end by a hydroxyl group
In membranes, the hydroxyl group interacts with phospholipid heads
Molecules that have both hydrophobic and hydrophilic properties
Amphipathic
Integral membrane proteins
Largely nonpolar
Span the lipid bilayer
(a & b)
Peripheral membrane proteins
Primarily bound by electrostatic and hydrogen-bonding
Largely polar external residues
(c & d)
Hydrophobic attachment
Bound by a fatty acid to the membrane
(e)