Chapter 12 And 10 Flashcards
Discovered DNA stores and transfers genetic info
Avery
Showed genetic info passes from one cell to another
Griffith
Confirmed genetic material is DNA
Hershey and chase
Showed DNA as a double helix
Franklin
Built first model of DNA
Watson and crick
Chargiff’s rule
A=T G=C
Building block of DNA
Nucleotide
3 parts of a nucleotide
Deoxyribose sugar. Phosphate group. Nitrogen bases
2 categories of nitrogen bases
Purines and pyrimidines
2 purines
Adenine guanine
2 pyrimidines
Thymine and cytosine
Shape of DNA
Double helix twisted ladder
Make up sides of DNA ladder
Deoxyribose sugar and phosphate
Holds nitrogen bases together
Weak hydrogen bonds
Where nitrogen bases branch from sides of ladder
Deoxyribose
Base pairing rule
Adenine to thymine and cytosine to guanine
The process by which DNA is copied
DNA replication
Step 1 of DNA replication
DNA double helix unwinds
Step 2
Enzymes break hydrogen bonds separating DNA into 2
Step 3
Each 1/2 serves as a template for new complimentary strand
Step 4
Free nucleotide match to halves by an enzyme called DNA polymerase
Step 5
2 identical DNAs are formed
Problems when cell is too big
Difficult to transport nutrients and wastes
Initiates cell division
The nucleus
Longest part of the cell cycle
Interphase 90%
3 steps of interphase
G1 S G2
Cell grows DNA is chromatin
G1
When DNA replication occurs
S
Sister chromatids
2 identical lengths of DNA
Centromeres
Holds chromatin together
When organelles replicate
G2
Mitosis
Nuclear division
4 phases of mitosis
Prophase metaphase Anaphase telophase
Difference in plant and animal cells
Animal- centrioles
When spindle forms chromosomes are visible as sister chromatids nuclear membrane disappears
Prophase
Metaphase
Chromosomes line up at the middle of the cell
Anaphase
Centromeres split and chromosomes travel 2 opposite poles
When chromosomes spread out spindle disappears. Nucleotide reappears
Telophase
Forms 2 new nuclear membranes
ER
Cytokinesis
Division of cytoplasm
Cytokinesis in animals
Cytoplasm pinched together
Cytokinesis in plants
Cell plate forms that becomes cell wall
Protein that regulates timing of cell cycle
Cyclins
Cancer
Uncontrollable growth of the cell resulting in tumors
Damaged caused by cancer
Damage surrounding tissue. Break loose and to spread to other parts of the body. Disrupt normal cell activities
Defective gene
Halts the cell cycle
Stem cells
Unspecialized cells that can differentiate