Chapter 11 Vocabulary Flashcards
Adenylyl Cyclase
An enzyme that converts ATP to cyclic AMP in response to a signal
Amplification
The strengthening of stimulus energy for transduction
Apoptosis
Controlled cell suicide program, brought on by signals that trigger activation of a cascade of suicide proteins destined to die
Biofilm
Surface-coating colony of one or more species of prokaryotes that engage in metabolic cooperation
Cyclic AMP
Cyclic adenosine mono phosphate, ring-shaped molecule made from ATP (common intracellular signaling molecule: second messenger in eukaryotic cells). + regulator of bacterial operons
Cytoplasm
Contents of cell, exclusive of the nucleus and bounded by plasma membrane
Epinephrine
Catecholamine that when secreted as hormone (by adrenal medulla) mediated f or f responses (short terms stress). AKA adrenaline
G Protein
GTP-binding protein relaying signals from membrane receptor (G protein-coupled receptor) to other signal tranduction protein inside the cell
Gap junction
Type of intercellular junction in animals allowing passage of materials between cells
Glycogen
Extensively branches glucose storage polysaccharide (found in liver and muscle) AKA muscle equivalent of starch
Growth factor
- Protein must be present in extracellular environment for growth and normal development of certain types of cells
- Local regulator on nearby cells to stimulate proliferation and differentiation
Inositol tri-phosphate (IP3)
2nd Messenger functioning as intermediate between non steroid hormones and 3rd messenger (rise in cytoplasmic Ca2+ concentration)
Ligand
Molecule binds specifically to another molecule, usually a larger one
Ligand-gated Ion Channel
Protein pore in cellular Membranes opening or closing in response to signaling chemicals, it allows for block or flow of ions
Local Regulator
Molecule secreted that influences cells near secretion site
Nitric Oxide (NO)
Gas produced by many types of cells function as local regulators and neurotransmitters
Protein kinase
Enzyme that transfers phosphate groups from ATP to protein, phosphorylating the protein
Protein Phosphatase
Enzyme that removes phosphate groups from proteins, therefore dephosphorylating it, often functions to reverse effects of protein kinase
Receptor Tyrosine Kinase
Receptor protein in membrane whose intercellular part can catalyze the transfer of phosphate group from ATP to another protein. Respond to binding by dimerizing and phosphorylating a tyrosine of other receptor in dimer (then activates signal transduction proteins)
Second messenger
Small, non-protein, water-soluble molecule or ion or cyclic AMP, relaying a signal to cell interior in response to signaling molecules bound by signal receptor protein
Signal transduction pathway
Series of steps that link mechanical or chemical stimulus to specific response
Testosterone
Steroid hormone required for male reproductive system development, secondary sex characteristics (major androgen in mammals)
Transcription Factor
Regulatory protein binding to DNA and affecting transcription of specific genes
Transduction
- Type of horizontal gene transfer which viruses carry bacteria DNA from one host cell to another
- Cellular communication (conversion of signal from outside to form that can bring response)