chapter 11 - nervous system; part 5 Flashcards
what are the 3 components of a chemical synapses?
- the enlarged ends of the axon are the presynaptic terminals containing synaptic vesicles
- the postsynaptic membranes contain receptors for the neurotransmitters
- the synaptic cleft is a space separating the presynaptic and postsynaptic membranes
what does an action potential arriving to a presynaptic terminal do?
it causes the release of a neurotransmitter, which diffuses across the synaptic cleft and binds to the receptors of the postsynaptic membrane
what are the effects of the neurotransmitter on the postsynaptic membrane is stopped in several ways?
- it is broken down by an enzyme
- it is taken up by the presynaptic terminal
- it diffuses out of the synaptic cleft
what is an excitatory postsynaptic potential (EPSP)?
it is a depolarizing graded potential of the postsynaptic membrane; it can be caused by an increase in membrane permeability to NA+
what is an inhibitory postsynaptic potential (IPSP)?
it is a hyperpolarizing graded potential of the postsynaptic membrane; it can be caused by an increase in membrane permeability to k+ or Cl-
presynaptic inhibition
decreases a neurotransmitter release
presynaptic facilitation
increases neurotransmitter release
spatial summation
occurs when two or more presynaptic terminals simultaneously stimulate a postsynaptic neuron
temporal summation
occurs when two or more action potentials arrive in succession at a single presynaptic terminal
inhibitory and excitatory presynaptic neurons
can converge on a postsynaptic neuron; the activity of the postsynaptic neuron is determined by the integration of the EPSPs and IPSPs produced in the postsynaptic neuron
convergent pathways
have many neurons synapsing with a few neurons
divergent pathways
have a few neurons synapsing with many neurons