chapter 11 - nervous system; part 4 Flashcards
what is a graded potential?
a small change in the resting membrane potential that is confined to a small area of the plasma membrane; graded potentials can summate, or add together
what could an increase in membrane potential to NA+ cause?
it can cause graded depolarization, and an increase in membrane permeability to k+ or cl- can result in graded hyperpolarization
when is the term graded potential used?
it is used because a stronger stimulus produces a greater potential change than a weaker stimulus
why does a graded potential decrease?
it decreases in magnitude as the distance from the stimulation increases
what is an action potential?
it is a larger change in the resting membrane potential that spreads over the entire surface of the cell
what is a threshold?
it is the membrane potential at which a graded potential depolarizes the plasma membrane sufficiently to produce an action potential
what happens when an action potential occurs?
it occurs in an all-or-none fashion; if action potentials occur, they are of the same magnitude, no matter how strong the stimulus
depolarization
occurs as the inside of the membrane becomes more positive because NA 1 diffuse into the cell through voltage-gated ion channels
repolarization
a return of the membrane potential toward the resting state; it occurs because voltage-gated NA+ channels close and Na+ diffusion into the cell slows to resting levels and because voltage-gated K+ channels continue to open and K+ diffuse out of the cell
what is the after potential?
it is a brief period of hyperpolarization following repolarization
absolute refractory period
it is the time during an action potential when a second stimulus, no matter how strong, cannot initiate another action potential
relative refractory period
follows the absolute refractory period and is the time during which a stronger-than-threshold stimulus can evoke another action potential
subthreshold
it is a stimulus that produces only a graded potential
what does a threshold stimulus cause?
it causes a graded potential that reaches threshold and results in a single action potential
submaximal stimulus
it is a greater than a threshold stimulus and weaker than a maximal stimulus; the action potential frequency increases as the strength of the submaximal stimulus increases
maximal/supramaximal stimulus
this stimulus produces a maximum frequency of action potentials
what can an action potential generate?
it can generate local currents, which stimulate voltage-gated NA+ channels in adjacent regions of the plasma membrane to open, producing a new action potential
propagation in an unmyelinated axon
action potentials are generated immediately adjacent to previous action potentials
propagation in a myelinated axon
action potentials are generated at successive nodes of ranvier
what are electrical synapses?
they are gap junctions in which tubular proteins called connexons allow local currents to move between cells; at an electrical synapses, an action potential in one cell generates a local current that causes an action potential in an adjacent cell