Chapter 11 Gene Expression and Regulation Flashcards
Anticodon
A sequence of three bases in transfer RNA that is complementary to the three bases of a codon messenger RNA.
Codon
A sequence of three bases of messenger RNA that specifies a particular amino acid to be incoprated into a protein; certain codons also signals the beginning or end of protein synthesis.
Deletion Mutation
A mutation in which one or more pairs of nucleotides are removed from a gene.
Gene
A unit of herdity that encodes the information needed to specify the amino acid sequence of proteins and hence particular traits; a functional segment of DNA located at a particular place on a chromosone.
Genetic Code
The collection of cdons of messenger RNA (mRNA), each of which directs the incorporation of particular amino acid into a protein during protein synthesis.
Insertion Mutation
A mutation in which one or more pairs of nucleotides are inserted into a gene.
Messenger RNA (mRNA)
A strand of RNA, complementary to the DNA of a gene, that conveys the genetic information in DNA to the ribosomes to be used during protein synthesis; sequences of three bases (codons) in mRNA specify particular amino acids to be incorporated into a protein.
Mutation
A change in the base sequence of DNA in a gene; normally refers to a genetic change significant enough to alter the appearance or function of the organism.
Nucleotide Substitution
A mutation that replaces on nucleotide in a DNA molecule with another; for example, a change from an adenine to a guanine.
Point Mutation
A mutation in which a single base pair in DNA has been changed.
Promoter
A specific sequence of DNA to which RNA polymerase binds, initiating gene transcription.
Ribonucleic Acid (RNA)
A molecule composed of a ribose nucleotides, each of which consists of a phosphate group, the sugar ribose, and one of the bases adenine, cytosine, guanine, or uracil; transfers herditary instructions from the nucelus to the cytoplasm; also the genetic material of some viruses.
Ribosomal RNA (rRNA)
A type of RNA that combines with proteins to form ribosomes.
Ribosome
An organelle consisting of two subunits, each composed of ribosomal RNA and protein; the bases of messenger RNA is translated into the sequence of amino acids in a protein.
RNA Polymerase
In RNA synthesis, an enzyme that catalyzes the bonding of free RNA nucleotides into a continous strand, using RNA nucleotides that are complementary to those of a strand of DNA.
Start Codon
The first AUG codon in a messenger RNA molecule.
Stop Codon
A codon in messenger RNA that stops protein synthesis and causes the completed protein chain to be released from the ribosome.
Template Strand
The strand of the DNA doble helix from which RNA is transcribed.
Transcription
The synthesis of an RNA molecule from a DNA template.
Transfer RNA (tRNA)
A type of RNA that binds to a specific amino acid byt means of a set of three bases (the anticodon) on the tRNA that are complementary to the messenge RNA (mRNA) codon for that amino acid; carries its amino acid to a ribosome during protein synthesis, recognizes a codon of mRNA, and positions its amino acid for incorporation into the growing protein chain.
Translation
The process whereby the sequence of bases of messenger RNA (mRNA) is converted into the sequence of amino acids of a protein.