Chapter 11 Flashcards
aden/o
gland
adren/o
adrenal/o
adrenal gland
andr/o
male
crin/o
to secrete
dips/o
thirst
gluc/o
glucos/o
glyc/o
glycos/o
sugar
hormon/o
hormone (an urging on)
ket/o
keton/o
ketone bodies
pancreat/o
pancreas
thym/o
thymus gland
thyr/o
thyroid/o
thyroid gland (shield)
adrenal glands
suprarenal glands
located above each kidney
adrenal cortex secretes steroid hormones
adrenal medulla secretes epinephrine and norepinephrine
steroid hormones
regulate carbohydrate metabolism and salt and water balance
some effect on sexual characteristics
includes the glucocorticoids, mineralocorticoids, and androgens
epinephrine
norepinephrine
affect sympathetic nervous system in stress response
ovaries
located one on each side of the uterus in the female pelvis, functioning to secrete estrogen and progesterone
estrogen
progesterone
responsible for the development of female secondary sex characteristics and the regulation of reproduction
pancreas (islets of Langerhans)
located behind the stomach in front of the first and second lumbar vertebrae, functioning to secrete insulin and glucagon
insulin
glucagon
regulate carbohydrate metabolism
parathyroid glands
located on the posterior aspect of the thyroid gland in the neck, functioning to secrete parathyroid hormone (PTH)
parathyroid hormone (PTH)
regulates calcium and phosphorous metabolism
pineal gland
located in the center of the brain, functioning to secrete melatonin and serotonin
melatonin
exact function unknown
affects onset of puberty
serotonin
a NT that serves as the precursor to melatonin
pituitary gland
hypophysis
located at the base of the brain
anterior pituitary secretes thyroid-stimulating hormone, adrenocorticotropic hormone, follicle-stimulating hormone, luteinizing hormone, melanocyte-stimulating hormone, growth hormone, and prolactin
posterior pituitary releases antidiuretic hormone (ADH, vasopressin) and oxytocin
thyroid-stimulating hormone (TSH)
stimulates secretion from thyroid gland
adrenocorticotropic hormone (ACTH)
stimulates secretion from adrenal cortex
follicle-stimulating hormone (FSH)
initiates growth of ovarian follicle
stimulates secretion of estrogen in females and sperm production in males
luteinizing hormone (LH)
causes ovulation
stimulates secretion of progesterone by corpus lute
causes secretion of testosterone in testes
melanocyte-stimulating hormone (MSH)
affects skin pigmentation
growth hormone (GH)
influences growth
prolactin (lactogenic hormone)
stimulates breast development and milk production during pregnancy
antidiuretic hormone (ADH)
influences the absorption of water by kidney tubules
oxytocin
influences uterine contraction
testes
located one on each side within the scrotum in the male, functioning to secrete testosterone
testosterone
affects masculinization and reproduction
thymus gland
located in the mediastinal cavity anterior to and above the heart, functioning to secrete thymosin
thymosin
regulates immune response
thyroid gland
located in front of the neck, functioning to secrete triiodothyronine, thyroxine, and calcitonin
triiodothyronine (T3)
thyroxine (T4)
known as the thyroid hormones
regulate metabolism
calcitonin
regulates calcium and phosphorus metabolism
exopthalmos
exopthalmus
protrusion of one or both eyeballs, often because of thyroid dysfunction or a tumor behind the eyeball
glucosuria
glycosuria
glucose (sugar) in the urine
hirsutism
shaggy
an excessive growth of hair especially in unusual places (e.g. a woman with a beard)
hypercalcemia
an abnormally high level of calcium in the blood
hypocalcemia
an abnormally low level of calcium in the blood
hyperglycemia
high blood sugar
hypoglycemia
low blood sugar
hyperkalemia
an abnormally high level of potassium in the blood
hypokalemia
deficient level of potassium in the blood
hypernatremia
excessive level of sodium ions in the blood
hyponatremia
low level of sodium ions in the blood
hypersecretion
abnormally increased secretion
hyposecretion
decreased secretion
ketosis ketoacidosis diabetic ketoacidosis (DKA)
presence of an abnormal amount of ketone bodies (acetone, beta-hydroxybutyric acid, and acetoacetic acid) in the blood and urine indicating an abnormal utilization of carbohydrates as seen in uncontrolled diabetes and starvation
metabolism
all chemical processes in the body that result in growth, generation of energy, elimination of waste, and other body functions
polydipsia
excessive thirst
polyuria
excessive urination
Cushing syndrome
collection of signs and symptoms caused by an excessive level of cortisol hormone from any cause, such as a result of excessive production by the adrenal gland (often caused by a tumor), or more commonly as a side effect of treatment with glucocorticoid (steroid) hormones such as prednisone for asthma, RA, lupus, or other inflammatory diseases
symptoms include upper body obesity, facial puffiness (moon-shaped appearance), hyperglycemia, weakness, thin and easily bruised skin with striae (stretch marks), hypertension, and osteoporosis
adrenal virilism
excessive output of the adrenal secretion of androgen (male sex hormone) in adult women owing to tumor tumor or hyperplasia
evidenced by amenorrhea (absence of menstruation), acne, hirsutism, and deepening of the voice
diabetes mellitus (DM)
metabolic disorder caused by an abnormal utilization of insulin secreted by the pancreas
evidenced by hyperglycemia and glucosuria
insulin
hormone secreted by the beta cells of the islets of Langerhans of the pancreas responsible for regulating the metabolism of glucose
type 1 diabetes mellitus
diabetes in which there is no beta cell production of insulin - the patient is dependent on insulin for survival
type 2 diabetes mellitus
diabetes in which the body produces insulin, but not enough, or there is insulin resistance (a defective use of the insulin that is produced) - the patient usually is not dependent on insulin for survival
hyperinsulinism
condition resulting from an excessive amount of insulin in the blood that draws sugar out of the bloodstream, resulting in hypoglycemia, fainting, and convulsions
often caused by an overdose of insulin or by a tumor of the pancreas
pancreatitis
inflammation of the pancreas
hyperparathyroidism
hypersecretion of the parathyroid glands, usually caused by a tumor
hypoparathyroidism
hyposecretion of the parathyroid glands
pituitary gland (hypophysis)
considered the master gland because it secretes hormones that regulate the function of other glands, such as the thyroid gland, adrenal glands, ovaries, and testicles
acromegaly
disease characterized by enlarged features, especially the face and hands, caused by hypersecretion of the pituitary hormone after puberty, when normal bone growth has stopped
most often caused by a pituitary tumor
diabetes insipidus
condition of abnormal increase in urine output most commonly caused by inadequate secretion of pituitary antidiuretic hormone (vasopressin)
symptoms include polyuria and polydipsia
urine appears colorless due to the inability of the kidneys to concentrate urine
pituitary dwarfism
condition of congenital hyposecretion of GH slowing growth and causing a short yet proportionate stature (not affecting intelligence) - often treated during childhood with GH
pituitary gigantism
condition of hypersecretion of GH during childhood bone development that leads to an abnormal overgrowth of bone, especially of the long bones
most often caused by a pituitary tumor
goiter
enlargement of the thyroid gland caused by thyroid dysfunction, tumor, lack of iodine in the diet, or inflammation
hyperthyroidism
Graves disease
thyrotoxicosis
condition of hypersecretion of the thyroid gland characterized by exophthalmia, tachycardia, goiter, and tumor
hypothyroidism
condition of hyposecretion of the thyroid gland causing low thyroid levels in the blood that result in sluggishness, slow pulse, and often obesity
myxedema
advanced hypothyroidism in adults characterized by sluggishness, slow pulse, puffiness in the hands and face, and dry skin
cretinism
condition of congenital hypothyroidism in children that results in a lack of mental development and dwarfed physical stature
the thyroid gland is either congenitally absent or imperfectly developed
blood sugar (BS) blood glucose
measurement of the level of sugar (glucose) in the blood
fasting blood sugar (FBS)
measurement of blood sugar level after a fast of 12 hours
postprandial blood sugar (PPBS)
measurement of blood sugar level after a meal, commonly after 2 hours
glucose tolerance test (GTT)
measurement of the body’s ability to metabolize carbohydrates by administering a prescribed amount of glucose after a fasting period, then measuring blood and urine for glucose levels every hour thereafter - usually for 4-6 hours
glycohemoglobin
molecule (fraction) in Hb that rises in the blood as a result of an increased level of blood sugar
it is a common blood test used in diagnosing and treating diabetes
also known as glycosylated Hb (HbA1c)
electrolytes
measurement of the level of specific ions (sodium, potassium, carbon dioxide, and chloride) in the blood
electrolyte balance is essential for normal metabolism
thyroid function study
measurement of thyroid hormone levels in blood plasma to determine efficiency of glandular secretions, including T3, T4, and TSH
urine sugar and ketone studies
chemical tests to determine the presence of sugar or ketone bodies in the urine
used as a screen for diabetes
computed tomography (CT)
CT of the head is used to obtain a transverse view of the pituitary gland
magnetic resonance imaging (MRI)
non-ionizing images of MR are useful in identifying abnormalities of pituitary, pancreas, adrenal, and thyroid glands
sonography
sonographic images are used to identify endocrine pathology, such as with thyroid ultrasound
thyroid uptake and image
nuclear image involving scan of the thyroid to visualize the radioactive accumulation of previously ingested isotopes to detect thyroid nodules or tumors
adrenalectomy
excision of adrenal gland
hypophysectomy
excision of pituitary gland
pancreatectomy
excision of pancreas
parathyroidectomy
excision of parathyroid gland
thymectomy
excision of thymus gland
thyroidectomy
excision of thyroid gland
continuous subcutaneous insulin infusion (CSII)
insulin pump therapy
use fo an insulin-delivery device worn on the body (usually the abdomen) that subcutaneously infuses doses of insulin programmed according to the individual needs of the diabetic patient
radioiodine therapy
use of radioactive iodine to treat disease, such as to eradicate thyroid tumor cells
antihypoglycemic
drug that raises blood glucose
antithyroid drug
agent that blocks the production of thyroid hormones
used to treat hyperthyroidism
hormone replacement
drug that replaces a hormone deficiency
hypoglycemic
antihyperglycemic
drug that lowers blood glucose