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Endo Final > Chapter 10- Substance P (FEW Q's) > Flashcards

Chapter 10- Substance P (FEW Q's) Flashcards

1
Q

What are the TWO sites of synthesis for SUBSTANCE P?

A

CNS/PNS

Neuropeptide

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2
Q

What is the FUNCTION of SUBSTANCE P?

A

transmit pain

transmits info about tissue damage to CNS

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3
Q

Information about PAIN transmitted by SUBSTANCE P binds to the _________ receptor

A

neurokinin-1

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4
Q

Substance P

________ heart rate
Stimulates ________

A

INCREASES heart rate

Stimulates VASODILATION

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5
Q

Substance P plays a role in INFLAMMATORY DISEASE in which THREE systems?

A

respiratory
gastrointestinal
musculoskeletal

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6
Q

What FOUR INFLAMMATORY processes are the result of Substance P?

A

eczema
fibromyalgia
low back pain
arthritis

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7
Q

PTSD and Major Depression are associated with Elevated Substance P concentrations and elevated ____________ concentrations

A

cerebrospinal fluid

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8
Q

Elevated Substance P levels are involved in ____________ (2)

A

major depression

PTSD

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Endo Final (4 decks)

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