Chapter 10 Physiology and Histology of the Skin Flashcards

1
Q

Acid mantle

A

Protective barrier made up of sebum, lipids, sweat, and water

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2
Q

Barrier function

A

Skins mechanism that protects us from irritation and intercellular transepidermal water loss

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3
Q

Intercellular matrix

A

Lipid substances between corneum cells that protect the cells from water loss and irritation

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4
Q

Epidermal Growth Factor (EGF)

A

Hormone that stimulates cells to reproduce and heal

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5
Q

Fibroblast

A

Cells that stimulate cells, collagen, and amino acids that form proteins (stimulating cells)

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6
Q

Arrector pili muscle

A

Small, involuntary muscles in the base of the hair follicle that cause goose flesh when the appendage contracts, sometimes called goose bumps and papillae

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7
Q

Langerhans immune cell

A

Guard cells of the immune system that sense unrecognized foreign invaders, such as bacteria, and then process these antigens for removal through the lymph system

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8
Q

Pore

A

Tube like opening for sweat glands on the epidermis

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9
Q

Sebum

A

Oil that provides protection for the epidermis from external factors and lubricates both the skin and hair

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10
Q

Keratin

A

Fibrous protein of cells that is also the principal component of skin, hair, and nails; provides resiliency and protection

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11
Q

Epidermis

A

Outermost layer of the skin; a thin protective layer with many cells, mechanisms, and nerve endings. It is made up of 5 layers

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12
Q

Dermis

A

Also known as the derma, corium, cutis, or true skin; support layer of connective tissue, collagen, and elastin below the epidermis

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13
Q

Subcutaneous layer

A

Also known as hypodermis; subcutaneous adipose tissue located beneath the dermis; a protective cushion and energy storage for the body

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14
Q

Reticular layer

A

Deeper layer of the dermis that supplies the skin with oxygen and nutrients; contains fat cells, blood vessels, suboriferous (sweat) glands, hair follicles, lymph vessels, arrector pili muscles, sebaceous (oil) glands, and nerve endings

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15
Q

Papillary layer

A

Top layer of the dermis next to the epidermis

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16
Q

Stratum corneum

A

Outmost layer of the epidermis, composed of corneocytes; also known as the horny layer

17
Q

Stratum lucidum

A

Clear, transparent layer of the epidermis under the stratum corneum; thickest on the palms of hands and soles of feet

18
Q

Stratum granulosum

A

Layer of the epidermis composed of cells filled with keratin that resembles granules; replaces cells shed from the stratum corneum; also known as the granular layer

19
Q

Stratum spinosum

A

Layer of the epidermis above the stratum germinativum containing desmosomes, the intercellular connections made of proteins; also known as the spiny layer

20
Q

Stratum germinativum

A

Active layer of the epidermis above the papillary layer of the dermis; cell mitosis takes place here that produces new epidermal skin cells and is responsible for growth; also known as basal cell layer

21
Q

Leukocytes

A

White blood cells that have enzymes to digest and kill bacteria and parasites. These white blood cells also respond to allergies

22
Q

Elastin

A

Protein fiber found in the dermis; gives skin its elasticity and firmness

23
Q

Adipose tissue

A

Fatty tissue found below the dermis that gives smoothness and contour to the body, contains fat for use as energy, and also acts as a protective cushion for the outer skin. Also know as subcutis tissue

24
Q

Apocrine glands

A

Coiled structures attached to hair follicles found in the underarm and genital areas that secrete sweat

25
Q

Eccrine glands

A

Sweat glands found all over the body with openings on the skins surface through pores; not attached to hair follicles; secretions do not produce an offensive odor

26
Q

Ceramides

A

Glycolipid materials that are a natural part of the skins intercellular matrix and barrier function

27
Q

Free radicals

A

Unstable molecules that cause inflammation, disease, and biochemical aging in the body, especially wrinkling and sagging of the skin

28
Q

Glycation

A

Binding of a protein molecule to a glucose molecule resulting in the formation of damaged, non functioning structures, known as advanced glycation end products

29
Q

Telangiectasia

A

Capillaries that have been damaged and are now larger, or distended, blood vessels; commonly called couperose skin

30
Q

Rosacea

A

Chronic condition that appears primarily on the cheeks and nose and is characterized by flushing, telangiectasia, and in some cases the formation of papules and postules