Chapter 10- microbial world Flashcards
Pathogen
A foreign invader that causes a disease
Virus
- smallest infectious agent
- considered biologically inert
- can’t be seen with light microscopes
- not all viruses affect humans
Biologically inert
Somewhere between simple biomolecules (proteins or DNA) and living organisms (bacteria)
Viruses do not meet the basic criteria scientists use to characterize life
- They do not perform metabolism
- They have no capacity for reproduction (by itself)
- Do not respond to stimuli
- No cellular composition (acellular)
- No complex growth
Acellular
No cellular composition
Eukaryotic cells
Membrane- bound nucleus
has organelles
Prokaryote cells
No membrane- bound nucleus
No organelles
Unicellular
Bacteriophage
Structure: rod and icosahedral (solid with 20 faces) mix
Only infect bacteria
Capsid
Protein she’ll that encloses the genetic material
- made up of smaller pieces called capsomeres
How do viruses replicate
By attaching to a host cell
Step 1: recognition
Viruses must be recognized by a cell to enter that cell
- usually contains specificity for one small group/ type of species
Envelope protein/spike protein needs to be recognized by the host cell’s receptors
Step 2: injection
The virus injects it’s genetic material or is brought into the cell (completely intact through endocytosis)
Step 3: transcription and translation
- The virus disassembles
- viral DNA is transcribed and translated by the host cell
Step 4: reassembly
Capsid protein re-assembles and releases new viral particles when there are many copies of viral DNA
- sometimes this destroys the cells
Lytic cycle
Host cell is terminated (lyses) at the end or replication cycle
- happens once many viruses have been generated
Lysogenic cycle
Rather than hijacking the cell, the virus inserts its viral DNA into the host’s genome creating a prophage
- cell continues to replicate, where the DNA remains silent
- host cell is not destroyed
- an environmental factor causes a switch into the lyric cycle causing the infected cell to lyse
Receptors
Allow virus to enter and exit without damaging the cell
Antibiotic
Inhibits then growth of or destroys bacteria
Shapes of bacteria
Cocci (ball)
Bacilli (rod-shaped)
Spirilla (spiral-shaped)
Shapes/2
Strepto: chain
Diplo: two
Staphylo: bunched together
Horizontal gene transfer
Exchanging genetic material
Conjugation
Plasmids are transmitted through pili
Binary fission
Produces two identical daughter cells
-begins at origin of replication
Cell elongates
-once there are two copies cell pinches in the middle
Bioremediation
Use of fungi to decompose pollutants in the soil