Chapter 10- microbial world Flashcards
Pathogen
A foreign invader that causes a disease
Virus
- smallest infectious agent
- considered biologically inert
- can’t be seen with light microscopes
- not all viruses affect humans
Biologically inert
Somewhere between simple biomolecules (proteins or DNA) and living organisms (bacteria)
Viruses do not meet the basic criteria scientists use to characterize life
- They do not perform metabolism
- They have no capacity for reproduction (by itself)
- Do not respond to stimuli
- No cellular composition (acellular)
- No complex growth
Acellular
No cellular composition
Eukaryotic cells
Membrane- bound nucleus
has organelles
Prokaryote cells
No membrane- bound nucleus
No organelles
Unicellular
Bacteriophage
Structure: rod and icosahedral (solid with 20 faces) mix
Only infect bacteria
Capsid
Protein she’ll that encloses the genetic material
- made up of smaller pieces called capsomeres
How do viruses replicate
By attaching to a host cell
Step 1: recognition
Viruses must be recognized by a cell to enter that cell
- usually contains specificity for one small group/ type of species
Envelope protein/spike protein needs to be recognized by the host cell’s receptors
Step 2: injection
The virus injects it’s genetic material or is brought into the cell (completely intact through endocytosis)
Step 3: transcription and translation
- The virus disassembles
- viral DNA is transcribed and translated by the host cell
Step 4: reassembly
Capsid protein re-assembles and releases new viral particles when there are many copies of viral DNA
- sometimes this destroys the cells
Lytic cycle
Host cell is terminated (lyses) at the end or replication cycle
- happens once many viruses have been generated
Lysogenic cycle
Rather than hijacking the cell, the virus inserts its viral DNA into the host’s genome creating a prophage
- cell continues to replicate, where the DNA remains silent
- host cell is not destroyed
- an environmental factor causes a switch into the lyric cycle causing the infected cell to lyse
Receptors
Allow virus to enter and exit without damaging the cell
Antibiotic
Inhibits then growth of or destroys bacteria