Chapter 10: Cell Cycle and Cell Division Flashcards

1
Q

What processes does cell division define?

A
  • REPRODUCTION
  • DEVELOPMENT
  • MAINTENANCE OF ORGANS
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2
Q

What is reproduction?

A

SEXUAL REPRODUCTION IS WHEN A FEMALE SEX CELL IS FUSING WITH A MALE SEX CELL
• FERTILIZATION
THEN THE CELL DIVIDES

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3
Q

Why is there an unlimited amount of sperm?

A

UNLIMITED AMOUNT OF SPERM IS DUE TO MITOSIS

DIVIDE INTO A CELL DIVISION, MEIOSIS, TO BECOME SPERM

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4
Q

Why are tissues able to repair and maintain themselves?

A

Cell Division allows tissues to repair and maintain their own cells

example: the lining of the small intestine is replaced every 5 days.

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5
Q

What parts of the tissue are responsible for repair and maintenance?

A

The Erythrocyte, leukocyte, and platelets

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6
Q

Why don’t we run out of blood?

A

Cell division

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7
Q

What causes cancer?

A

Overwhelming, uncontrolled mitosis

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8
Q

What does cell division consist of?

A

DNA replication, separation of DNA, and regulation/control

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9
Q

What are Histones?

A

Histones are basic proteins, and their positive charges allow them to associate with DNA, which is negatively charged. Some histones function as spools for the thread-like DNA to wrap around.

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10
Q

What are chromosomes associated with? (2)

A

DNA and proteins

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11
Q

Haploid vs Diploid cells

A

Diploid cells, such as body cells, have two copies of chromosomes (2n), a total of 46 chromosomes. Haploid cells, such as sex cells, have 23 chromosomes each (n)

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12
Q

Chromosomes vs. chromatid

A

Each molecule is called a chromatid (initially attached all along their lengths by adhesive protein complexes called cohesins) and the two of the molecules are called a duplicated chromosome

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13
Q

Chromosome structure

A

Consists of 2 sister chromatids and a centromere in the middle

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14
Q

What does interphase consist of?

A

G1 (cell growth), G2 (cell preparation), S (DNA replication)

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15
Q

What is Mitosis and what does consist of?

A

Division of the nucleus

Prophase, Prometaphase, Metaphase, Anaphase, Telophase

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16
Q

What is Cytokinesis?

A

Actual cell division

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17
Q

What is the mitotic spindle?

A

Guide to make sure that the chromosomes are going in the correct path. Consists of Kinetochore microtubules, non-kinetochore microtubules, centrosomes ,spindle, microtubules, asters

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18
Q

What happens in Prophase?

A
  • Chromosomes condense
  • Nucleolous disappears
  • Mitotic spindle begins to form
19
Q

What are centrioles?

A

Structure: nine triplets of microtubules form one centriole
- two centrioles form one centrosome

Function - forms spindle fibers to separate chromosomes during cell
division

20
Q

What happens in Prometaphase?

A
  • Nuclear envelope breaks down
  • Kinetochore formation occurs
  • Microtubules are actually attaching to the centrometer
  • Some microtubules are physically attaching Kinetochore microtubules
  • NOT ATTACHED: nonkinetical. Makes sure the cell is stable
21
Q

Kinetochore structure

A

Protein structure on chromatids where the spindle fibers attach during cell division to pull sister chromatids apart.

22
Q

What happens during metaphase?

A
  • Chromosomes perfectly align

- Distinct form of condensation

23
Q

What happens during Anaphase?

A

-Spindles separate from the straight line (from metaphase) as chromosomes

24
Q

What are non-Kinetochore microtubules?

A
  • Sliding of the nonkinetochore microtubules pushes poles apart increasing the total length of the spindle
  • The motor proteins from the microtubules are moving and attaching themselves. This shortens the microtubule.
25
By what process are the damaged cells in a wound replaced?
Mitosis
26
By what process are eggs formed?
Meiosis
27
By what process does a zygote develop into a multicellular organism?
Mitosis
28
In which process are identical daughter cells produced?
Mitosis
29
Which process reduces chromosome # of daughter cells?
Meiosis
30
What is the difference between Kinetochore microtubules and non-kinetochore microtubules?
- kinetochore: microtubules that attach to kinetochores at the centromere of sister chromatids - non: do not attach to kinetochores and continue elongating and overlapping
31
What happens during Telophase?
- Spindle disassembles - Chromosomes decondense - Nucleolus reappears - New nuclear envelope forms
32
What happens during Cytokinesis?
- The cytoplasm divides to produce two daughter cells - microfilaments form and contract to constrict the cell in the middle until the two cells separate. * *Same amount of genetic material**
33
How is the cell cycle regulated?
- Internal check points to prevent any phase from beginning before the completion of the previous phase - Hormones and growth factors are external factors to coordinate the cell cycle with the needs of the organism
34
What are the different ways that internal control is maintained? (4)
-Cyclin -Cyclin dependent kinase (CDK) >Cyclin dependent >Regulated by kinase/phospatase -G1-S transition checkpoint -G2-M transition checkpoint
35
What happens when cell division is unchecked?
• At first the cells have the same shape as the original shape as the other cells - Then as they grow, the shape changes - Extracellular matrix changes - Cells start to migrate: Metasisis - Spreading all over the body - Happens since the cells lose connection examples: cancer and tumors (organs grow more than the maximum size)
36
What is Meiosis?
- Process that produces gametes that are haploid (n) - Produce four cells that are genetically different - Sexual reproduction
37
Benefits of Meiosis?
- Replication - Crossing over/swapping of segments * *Benefit: Genetic diversity
38
What is the process of Meiosis?
- Start: Homologous chromosomes - Homologous chromosomes replicate - Exchange segments - First meiotic division - Second meiotic division
39
State Meiosis' two parts
-Meiosis I: prophase I, prometaphase I, metaphase I, anaphase I, telophase I --Meiosis II: prophase II, prometaphase II, metaphase II, anaphase II, telophase II
40
What happens in prophase I?
- Chomatids condense - Homologous pairs align - Chrosomes swap places (recombination: breaking and rejoining of DNA fragments) * *Genetic Diversity
41
What are homologous chromosomes held together by?
A protein complex called the synaptonemal complex
42
What happens in Metaphase I?
-Homologous chromosomes align at the equatorial plane -Independent assortment >>3 chromosomes, 2^3 ways to arrange them
43
Anaphase I and Telophase I
Anaphase I: two chromosomes separate and move toward opposite poles of the cell as a result of the action of the spindle. Telophase I: A nuclear envelope reforms around each chromosome set, the spindle disappears