Chapter 10 Flashcards
More than half of all antibiotics and semisynthetic drugs come from which of the following genera:
Streptomyces
Which of the following is the result of the action of cell wall inhibiting drugs?
Cells become more susceptible to osmotic pressure.
B-lactam antibiotics have an effect on which of the following types of cells?
bacterial cells
Semisynthetic drugs represent all of the following improvements except:
they work faster
Which of the following is a drug that specifically targets cell walls that contain arabinogalactan-mycolic acid?
Isoniazid
All of the following drugs affect the proper function of the ribosome expcept
polymyxin
All of the following are targets of drugs that inhibit protein synthesis except:
Interference with alanine-alanine bridges.
The scientist who coined the term “antibiotic” was
Fleming.
The most limited group of antimicrobial agents is the Blank drugs.
antiviral
Another term for the kirby-bauer test is the
diffusion susceptibility test
Which of the following is not true of inhibition?
The larger the zone the more resistant the organism is
Which of the following groups of drugs can become incorporated into the bones and teeth of a fetus
tetracyclines
All of the following are potentially serious side effects associated with, or caused by, antimicrobial drugs except
Blach hairy tongue
All of the following statements concerining development of antibiotic resistance are true except
resistant cells grow more efficiently and quickly that susceptible cells
B-lactamase production is an example of which of the following type of resistance
inactivation of the drug
proboicts
A,B, and C are correct
Most drugs that inhibit the synthesis of the cell wall act by
preventing the cross-linkage of NAM subunits
the type of atimicrobial drug that would be least toxic to humans is a drug that
inhibits the synthesis of the cell wall
Which of the following wok by inhibiting ergosterol synthesis?
Bothe A and B are correct
Sufonamides
A, B, and C are correct
Which of the following pathways is specifically inhibited by sulfonamides?
The conversion of PABA to dihydrofolic acid
Which of the following drugs inhibits nucleic acid synthesis specifically in prokaryotes?
quinolones
The cooperative activity of drugs such as B-lactam antibiotics and clavulanic acid, a B-lactamase
synergism
Alterations in the structure of which of the following are an important aspect of gram-negative bacterial resistance to antimicrobial drugs?
porins