Chapter 10

Question 1

SMC Proteins

Answer 1

Structural Maintenance Proteins:
- Cohesin
- Condensin
- Separase

Question 2

Do bacteria have histones?

Answer 2

No. They just have core proteins

Question 3

Do eukaryotes or bacteria undergo transcription faster?

Answer 3

Faster transcription in bacteria

Question 4

What is ubiquitination used for?

Answer 4

Protein degradation

Question 5

HAT

Answer 5

Histone Acetylation
- Opens (activates) DNA by exposing promoter regions

Question 6

HDAT

Answer 6

Histone Deacetylation
* Methylation!
- Closes (deactivates) DNA by hiding promoter regions

Question 7

Chromatin Remodeling Complexes

Answer 7

Reposition Nucleosome
Eject
Replace

Question 8

Histone Modifying Enzymes

Answer 8

Histone N-Tails are modified
- Cis
- Trans

Question 9

What is the Histone Code

Answer 9

The “code of conduct” for unrolling DNA

1. Modifications
2. Kinases
   -> 3. Trans reposition using bromodomain or chromodomain

Once you start to remodel, there will be a cascade of events (

Question 10

What do Kinase do?

Answer 10

Activate proteins that will do some kind of trans repositioning (using bromodomains or chromodomains) Kinase Phosphorylate