chapter 10 Flashcards

1
Q

What is a case control study?

A

compares the exposure histories of people with disease and people without disease

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2
Q

What is matching?

A

recruiting 1 or more controls who are demographically similar to each case

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3
Q

what is frequency matching?

A

similar group-level demographic characteristics

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4
Q

What is matched-pairs matching?

A

links each case to one or more controls with similar characteristics

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5
Q

what is overmatching?

A

statistical bias that can result from matching too many characteristics of cases to controls

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6
Q

What is minimizing bias?

A

a systematic flaw in the design or analysis that can cause to results of the study not to accurately reflect the truth about the source population

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7
Q

misclassification bias?

A

not correctly categorized, case and controls are mixed up or there is a problem with case definition or control definition

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8
Q

what is a recall bias?

A

occurs when cases and controls systematically have different memories of the past

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9
Q

what is the measure of association?

A

number that summarizes the relationship between an exposure and a disease outcome

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10
Q

what is the odds ratio?

A

odds of exposure - cases / odds of exposure - controls

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11
Q

what is a contingency table?

A

a row by column table that displays the counts of how often various combinations of events happen

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12
Q

What is the point estimate?

A

value of the statistic in a study population - ad/bc

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13
Q

what is OR =1

A

about the same

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14
Q

what is OR>1?

A

cases>controls - exposure = risky

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15
Q

OR<1 ?

A

cases> controls - exposure is protective

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16
Q

what is OR<1?

A

cases

17
Q

what does it mean when the confidence interval is less than 1 ?

A

protective

18
Q

what does it mean when the confidence interval is greater then 1?

A

risky

19
Q

What if the confidence interval overlaps?

A

it is not significant

20
Q

what is concordant pairs?

A

case/control have same exposure history

21
Q

what is discordant pairs?

A

case/ control have different exposure history

22
Q

What does a matched pair odds ratio do?

A

compares the number of pairs in which the case had the exposure and the control didn’t