Chapter 1 - INTRO Flashcards

1
Q

Which six elements account for the major weight of most organisms?

A

Hydrogen, carbon, nitrogen, oxygen, phosphorus and sulfur.

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2
Q

Give the structure building blocks of proteins, DNAs and RNAs.

A

Proteins are made up of amino acids: contain an amino group, a carboxyl group, a side chain, and a hydrogen atom attached to a central carbon atom
DNA is composed of nucleotides: a sugar (deoxyribose), a phosphate group, and a nitrogenous base.
RNA is also made up of nucleotides, but it contains sugar ribose instead of deoxyribose.

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3
Q

What are polysaccharides? Use what linkage?

A

Monosaccharides connected by a glycosidic bond; acetal linkage

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4
Q

Nucleotides are…

A

functional monomers used to prepare nucleic acid polymers.

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5
Q

Each nucleotide contains 3 things:

A

5 carbon sugar, heterocyclic containing nitrogen base, and at least one phosphate group.

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6
Q

Lipids are either _____ or contain significant nonpolar regions. This monomer is less ________. The simplest form are __________. The ____________ area major component of biological membranes.

A

nonpolar; systematic; fatty acids (FAs); Glycerophospholipids

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7
Q

What are the 2 common types of nucleic acids? How are nucleotides connected?

A

DNA and RNA; via 3’,5’-phosphodiester bonds

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8
Q

What does metabolism describe?

A

The synthesis/degradation of biomolecules coupled with the energy transferred, stored, & used (bioenergetics).

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9
Q

Energy transfer is both related to both ______ (rates) and _______ (spontaneity)

A

kinetics; thermodynamics

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10
Q

If delta G<0, the reaction is ________. If delta G=0, the reaction is _______. If delta G>0, the reaction is ______.

A

spontaneous; at equilibrium; nonspontaneous

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11
Q

What does delta G++ represent?

A

The activation barrier (Ea)

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12
Q

Cell are all classified as either _______ or _________. The membrane is __________. The cytoplasm describes everything enclosed by the plasma membrane including: _______ and _________.

A

prokaryotes; eukaryotes; semi-impermeable; organelles; cytosol

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13
Q

Prokaryotes are usually ________ organisms. List 4 things and give an ex.

A

single-celled; don’t have a nucleus regions but instead a nucleoid region, usually no internal membrane compartments, often have pili/flagella, high SA to volume ratio (easier to transport/traffic via simple diffusion); Escherichia coli

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14
Q

List 4 things about eukaryotic cells.

A

Have a single plasma membrane and a nucleus, much smaller SA to volume ratio (need mechanisms for active transport), most contain organelles, multicellular eukaryotes have differentiated cells/tissues

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15
Q

What is the nucelus?

A

A large membrane-enclosed region present in most eukaryotic cells that serves as its control center.

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16
Q

What is the nuclear envelope?

A

Is a double lipid bilayer, provides extra protection/security.

17
Q

Each linear nucleic acid sequence is called a _________. Most eukaryotes are ____ and contain two copies of each chromosome. Sex cells are ____ and contain one copy of each chromosome.

A

chromosome; diploid; haploid

18
Q

What serves as the location for DNA replication, RNA transcription and is highly regulated?

A

The nucleus.

19
Q

Describe the Endoplasmic reticulum (ER).

A

A network of membrane-enclosed folds which radiate outward from the nucleus.

20
Q

Where are ribosomes located in the ER? And what is their role?

A

The exterior surface; synthesize proteins from mRNA (translation).

21
Q

What is the lumen and their role?

A

The interior of the ER; collects/organizes proteins for cellular export via vesicles.

22
Q

What happens to the vesicles when the are exported from the ER?

A

They arrive at the Golgi apparatus, modified, reorganized, & packaged for transport (out of cell or other locations)

23
Q

What 2 things are involved in energy transduction?

A

Mitochondria and chloroplasts

24
Q

Name similarities b/w the mitochondria and chloroplasts.

A

Contain a double-membrane (inner, outer), inner membranes are highly-folded…increasing SA, inner membranes and their interior regions are critical for organelle function, both derived from ancient bacteria

25
Q

Define a vesicle.

A

A specialized, single membrane-enclosed region within a cell.

26
Q

What protects the cytosol?

A

Compartmentalization.

27
Q

Where are lysosomes found and their function and how.

A

Found in eukaryotic cells and used for cellular digestion; interior is highly acidic and contains many enzymes to break down macromolecules.

28
Q

What are Peroxisomes found and used for?

A

Found in animal (and some plant) cells and used to conduct oxidation reactions with H2O2.

29
Q

Where are Vacuoles found and their function?

A

Found in mature plant cells (and some protists) and used for storage.

30
Q

Is the cytoskeleton an organelle?

A

No

31
Q

CYTOSKELETON: What are the 3 types of protein filaments?

A

Actin filaments (microfilaments), Microtubules, Intermediate filaments.

32
Q

State something about actin filaments.

A

Most abundant protein in a cell.

33
Q

State 2 things about microtubules.

A

Thicker, stronger fibers of tubulin, packed in bundles. Serve as an internal skeleton and for directed movement (e.g. cilia).

34
Q

State 1 thing about Intermediate filaments.

A

Extend outward from nuclear envelope to help cell resist external stress.