Chapter 1- General Pharm. Flashcards
what is ADME in pharmacokinetics
Administration
Distribution
Metabolism and bio-transformation
Excretions pathways and rates
Whats the difference between dispensing and prescribing
dispensing is using the clinics internal drugs
prescribing is writing or calling a third party to fill the prescription
what needs to be on a prescription
Drug, DEA number, whether it is as written or can be substituted, who its for, how many refills, how many pills, the directions, and the information for the client (address, date, who its for)
how do you rate a controlled substance
they do it by how addictive the drug is. the DEA does it
when you prescribe you must have 7 items
- the vets name, address, phone number, DEA number,
- the clients name and address including signalment of the patient including species and name
- the name of the drug
- the sig- frequency, dose, route, and duration
- the number of refills
- the vets signature
- the date
whats on the prescription label
- name, address of the dispenser
- clients name
- animals name and species
- drug name, strength, and quantity
- date of order
- directions for use
- any refill information
- warning stickers
dose response curve
a time vs concentration curve
what is the area under the curve
it is the effective dose or therapeutic index
liver
the most common place that drugs are metabolized
1st pass effect
some drugs are metabolized by hepatocytes as they arrive in the portal circulation
x+30%