Chapter 1 Flashcards

foundations of neuroscience past, present and future

1
Q

first origins of brain being vital to life and the evidence of it

A

prehistoric ancestors: trepanation/skulls showing signs of healing

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2
Q

First known “HEART is the seat of the soul and memory”

A

Ancient Egypt

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3
Q

Clung to the heart centre/brain is radiator that cools the blood/tempered the seething heart

A

Aristotle’s view of the brain

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4
Q

View of the brain: hippocrates

A

correlation between structure and function/brain involved in sensation/brain is the seat of intelligence

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5
Q

Roman empire’s view of the brain

A

Galen: cerebrum, cerebellum, ventricles; which had 4 humour balance in the hollow ventricles

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6
Q

The renaissance view of the brain

A

Fluid mechanical theory of the brain’s function/philosophical mind-brain problem/descartes/fluids control movement by route of pineal gland

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7
Q

renaissance->17th and 18th centuries->19th century

A

discovery of white and grey matter; gyri, sulci and fissures

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8
Q

19th century

A

central nervous system and peripheral nervous system, nerves as wires, electrical and can generate electricity

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9
Q

CNS-Brain+SC

A

Cerebrum, cerebellum, brain stem—>Spinal cord

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10
Q

Bell and Magendie

A

Dorsal (incoming) and ventral roots (outgoing), 19th century

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11
Q

Pioneers of localization of function in the brain

A

Charles Bell

Marie-Jean-Pierre Flourens

Franz Joseph Gall

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12
Q

Marie-Jean-Pierre Flourens:

A

Experimental ablation method (systematically destroying a part of brain to observe what it affects.

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13
Q

Charles Bell

A

Cerebellum (origin of motor fibers)

Cerebrum (destination of sensory fibres)

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14
Q

Franz Joseph Gall

A

Phrenology: bumps on the surface of skull reflect brain surface and related personality traits/

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15
Q

Paul Broca

A

Broca region: the speech area (prefrontal cortex)

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16
Q

Nervous system evolution

A

natural selection (darwin), nervous systems of different species may share common mechanisms from common ancestors.

17
Q

Reductionist approach

A
  1. Molecular
  2. Cellular
  3. Systems
  4. Behavioural
  5. Cognitive
18
Q

Clinical (medical) neuroscience

A

Neurologist, psychiatrist, neurosurgeon, neuropathologist

19
Q

Experimental neuroscience

A

computational neuroscience

developmental neurobiologist

molecular neurobiologist
neuroanatomist
neurochemist
neuroethologist
neuropharmacologist
neurophysiologist
psychophysicist
physiological psychologists
20
Q

Scientific process

A
  1. Observation
  2. Replication
  3. Interpretation
  4. Verification
21
Q

Animals in neuroscience research/

A

Renewable resources

the more basic the process under investigation, the more distant the evolutionary relationship with humans

22
Q

3 moral responsibilities/governing body

A
  1. ensure that experiments are worthwhile and well planned
  2. Eliminate or minimize pain and distress to animal
  3. All possible alternatives must be considered first