Chapter 1 Flashcards
what are the leading causes of death in the U.S. according to the CDC?
- heart disease
- cancer
- unintentional injuries from COVID (poisoning, motor vehicle accident, overdose, downing, falls)
- COVID
- stroke
what are the leading causes of death in the world according to the WHO?
- heart disease
- stroke
- COPD
- lower respiratory infection
- neonatal conditions (developing countries)
what are the leading causes of death for low income countries?
- neonatal conditions
- lower respiratory infections
- ischemic heart disease
diseases are communicable (contagious)
what are the leading causes of death for high income countries?
- ischemic heart disease
- alzheimers
- stroke
more access to health care and diseases are not communicable (not contagious, preventable?)
disease
any disturbance of structure or function of the body (loss of homeostasis)
acute disease
contagious, caused by pathogen, 6 months or less
chronic disease
long lasting, more than 6 months (cancer/heart disease)
etiology
cause of disease
disease is due to…
structure or function gone wrong
structural disease
- structure changes in a cell, organ, etc.
- caused by lesions that occur in the body
- caused by external or internal mechanisms
- ex. unintentional COVID injuries, heart disease, alzheimers, cancer
functional disease
- no morphological abnormalities yet body functions are disturbed
- no visible lesions present initially (microscopic), over time structural changes will appear
- caused by physiological changes
- ex. hypertension, diarrheal diseases are both structural and functional
gross examination
can see with the naked eye
histologic examination
see changes under a microscope
lesion
change in DNA of the cell
structure and function are intimately related..
change in structure leads to change in function
pathology
study of structural and functional changes in body as a result of disease
pathologist
physician who specializes in diagnosing and classifying diseases by studying the morphology of cells and tissues
clinician
physician/health care professional that cares for patients
pathogenesis
abnormal creation
pathogen
organism causing disease
manifestation
expression of, physical result of disease
types of manifestation
- symptoms: something that is not measurable (subjective)
- signs: measurable, vitals (objective)
- lesion: characteristic structural changes in organs and tissues as a result of disease
- asymptomatic: without symptoms
predisposing
more likely to get a disease
categories of disease
- vascular
- infectious (inflammatory): COVID
- neoplastic: cancer, improper development of cells
- degenerative (deficiency): osteoporosis
- idiopathic: hypertension
- congenital
- allergic (autoimmune)
- traumatic
- endocrine (hormonal)
- metabolic
causes of disease
- exogenous: outside of body (physical, chemical, microbiologic)
- endogenous: inside of body (vascular, immunologic, metabolic)
- idiopathic: cause is unknown
- iatrogenic disease: disease caused by medical exam or treatment (side effect of drug)
- nosocomial disease: acquired from hospital environment (bacteria)
why do patients most often seek medical help?
due to a symptom
clinician gathers facts (workup) which include..
history, predisposing risk factor, physical exam, lab and diagnostic tests
prognosis
likely outcome/course the disease will take
- chances of complete recovery
- prediction of permanent loss of function
- probability of survival
complication
abnormal state that develops in person with disease
palliative care
treatments designed to relieve and manage symptoms
- may still receive treatment
- often serious chronic illness
- useful for all stages of a disease
hospice care
comfort care when cure is no longer possible
process of patient care is limited by..
- access to care
- nature of particular diseases
- clinicians ability to understand disease processes
time lag
application of new knowledge about disease processes and therapeutic interventions lags far behind discoveries (15-20 years)
obstacles to patient care
- time lag
- standards of practice are not universally adhered to
- type of facility
- bias
- mistrust in medical institutions