chap 14-16 Flashcards
NAME?
To separate: hematocrit- percentage by volume of red blood cells in a blood sample, determined by separating the red blood cells from the plasma
NAME?
Abnormal condition: leukocytosis- condition in which white blood cells are overproduced
Aneurysm
Abnormal expansion of a blood vessel wall
Angio-
Vessel: angiotensin- substance that constricts blood vessels
Angina
A condition, such as a severe sore throat, in which spasmodic attacks of suffocating pain occur
Ather-
Porridge: athersclerosis- deposits of plaque in arteries
Atherosclerosis
Accumulation of fatty substances on the inner linings of arteries
Brady-
Slow: bradycardia- abnormally slow heartbeat
Coronary blood vessels are supplied from what vessel?
Aorta
Diapedesis
Squeezing movement of leukocytes between the cells of blood vessel walls
Diastol-
Dilation: diastolic pressure- blood pressure when the ventricle of the heart is relaxed
Embol-
Stopper: embolism- a mass lodging in and obstructing a blood vessel
Erythr-
Red: erythrocyte- red blood cell
Hemo-
Blood: hemoglobin- red pigment responsible for the color of blood
How do you compute cardiac output?
The total volume of blood pumped by the ventricle per minute, or simply the product of heart rate (HR) and stroke volume (SV).
How do you compute heart rate?
Total bpm - your age
How do you diagnose the types of abnormal ECGs we discussed?
it will look abnormal
How do you compute stroke volume?
SV (stroke volume ) x BPM = CO (Cardiac Output)
Infarction
When a localized area of muscular tissue is dying or dead due to insufficient supply of blood (as occurs in a heart attack)
How is blood pressure regulated?
Monitored by Baroreceptors, Modified by Heart action, smooth muscle constriction, hormone action
Ischemia
A decrease in blood supply to a bodily organ, tissue, or part caused by constriction or obstruction of the blood vessels
Leukocytosis
Too many white blood cells in the blood
Leukopenia
Too few white blood cells in the blood
Pancytopenia
Too few red blood cells, white blood cells, and platelets usually associated with a bone marrow tumor or aplastic anemia
Papill-
Nipple: papillary muscle- small mound of muscle projecting into a ventricle of the heart
Phleb-
Vein: phlebitis- inflammation of a vein
Plasmin
Protein-splitting enzyme that can digest fibrin in a blood clot
Prolapse
The falling down or slipping out of place of an organ or part
Septicemia
A systemic disease caused by pathogenic organisms or their toxins in the blood stream (blood poisoning)
Syn-
Together: syncytium- mass of merging cells that act together
Systol-
Contraction: systolic pressure- blood pressure resulting from a single ventricular contraction
Tachy-
Rapid: tachycardia- abnormally fast heartbeat
Thromb-
Clot: thrombocyte- blood platelet involved in the formation of a blood clot
Thrombin
Blood-clotting enzyme that catalyzes formation of fibrin from fibrinogen
What are all the parts of the heart we discussed?
Chambers, valves, major blood vessels, papillary muscles, chordae tendinae, skeleton, conduction system, etc.
Two ways Compliment works
Opsination, Membrane Attack Complex
What are examples of non-protein nitrogenous substances?
Urea, uric acid, creatine
What are Starling’s forces?
Inword: Tissue Osmotic, Tissue Hydrostatic
What are the “resistance” vessels?
arterioles
What are the blood cell lineages? (mainly the top and bottom of the tree)
Erythroid, lymphocytes, and myelocytes
What are the different types of anemia?
Aplastic and hemolytic anemia, sickle cell and thalassemia anemia, and iron deficiency and pernicious anemia.
What are the 3 major intake vessels for the right atrium?
…
What are the distal steps of the extrinsic clotting pathways that we discussed?
…
What are the distal steps of the intrinsic clotting pathways that we discussed?
…
What are the key facts about basophils?
<1%, release Histamine (vasodilator) and Heparin (anticoagulant)
What are the key facts about eosinophils?
1-3%, Parasite defense
What are the key facts about lymphocytes?
25-33%, B,T, and NK cells, Specific immune response.
What are the key facts about monocytes?
3-9%, largest blood cells, leaves blood to become Macrophage, phagocytic
What are the key facts about neutrophils?
most abundant, very phagocytic, first to arrive at infection
What are the layers of the heart wall?
Myocardium, Endocardium
What are the major layers of a blood vessel wall?
Tunica interna, Media and Externa
What are the major plasma proteins?
Albumins, Globulins, Fibrogens
What are the parts of whole blood when spun down?
Plasma, buffy coat, red cells
What are the pericardial layers of the heart?
Fibrous, Visceral, Parietal pericardium
What are the S1 and S2 heart sounds caused by?
S1: AV Valves closing
What are the various types of WBCs?
Granulocytes (neutrophils, eosinophils, and basophils) and agranulocytes (monocytes and lymphocytes)
What causes aplastic and hemolytic anemia?
Radiation and toxic chemicals
What causes iron deficiency and pernicious anemia?
Lack of iron and inability to absorb B12
What chamber of heart responsible for pulmonary systolic pressure?
…
What chamber of heart responsible for systemic systolic pressure?
…
What do monocytes differentiate into?
macrophage
What do the chambers of the heart do?
Atriums: prime ventricles
What do the chordae tendineae of the heart do?
hold valves to they don’t prolapse
What do the major blood vessels of the heart do?
left and right coronary arteries originate near aortic valve, drain to coronary sinus in right atrium.
What do the papillary muscles of the heart do?
articulate heart valves
What do the valves of the heart do?
The Peanuts Might Attack! (Tricuspid, Pulmonary, Mitral, Aortic)
What do the waves in a normal ECG mean?
P Wave: Atrial Depolarization
What does the body make in low oxygen environments (e.g. high altitude)? Why?
RBCs
What does the conduction system of the heart do?
provides pathway for cardiac stimulation
What does the plasma protein Albumin do?
Most Common, Liver, Retains water
What does the plasma protein Fibrinogen do?
Liver, blood clotting
What causes sickle cell and thalassemia anemia?
Defective genes
What does the plasma protein Globulins do?
alpha and beta: liver, transports lipids and vitamins. Gamma: Lymphatic tissue, antibodies
What does the skeleton of the heart do?
provides rigid structure and electrical insulation to valves
What does the spleen do?
filter dead blood cells
What exactly causes blood to flow from one heart chamber to another?
Contraction of atrium and opening of AV Valve
What happens in capillaries?
substances are exchanged
What happens to the globin part of hemoglobin when broken down?
broken down into amino acids
What ion is critical for blood clotting?
Ca2+
What is a murmur?
Abnormal heart sound
What is blood typing and what are the major antigens and antibodies involved?
Determining the presence of surface antigens on the cell membranes of RBCs. Blood has antibodies against the opposite antigens (blood types)