Changes at birth with fetal circulation Flashcards
1
Q
at first breath
A
decreasing peripheral vascular resistance
2
Q
lung PG dehydrogenase
A
-destroys PGE2 from placenta
3
Q
what closes ductus arteriosus
A
O2 sensitive K channels, increased O2 in arterial blood
4
Q
clamping of placenta
A
low resistance placenta out of circulation
systemic vascular resistance increases
5
Q
over the next 6 weeks, why does PVR do down?
A
decreased muscular coat of pulmonary arterioles
lowers PVR
6
Q
what happens with the RV?
A
muscular right ventricle thins as total cardiac output drops and pulmonary resistance falls