Changes at birth with fetal circulation Flashcards

1
Q

at first breath

A

decreasing peripheral vascular resistance

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2
Q

lung PG dehydrogenase

A

-destroys PGE2 from placenta

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3
Q

what closes ductus arteriosus

A

O2 sensitive K channels, increased O2 in arterial blood

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4
Q

clamping of placenta

A

low resistance placenta out of circulation

systemic vascular resistance increases

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5
Q

over the next 6 weeks, why does PVR do down?

A

decreased muscular coat of pulmonary arterioles

lowers PVR

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6
Q

what happens with the RV?

A

muscular right ventricle thins as total cardiac output drops and pulmonary resistance falls

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