Ch.9: Adrenergic Drugs Flashcards

1
Q

esomolol is a shorter acting version of which drug?

A

atenolol

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2
Q

sympathetic action on respiratory system

A

dilates airways
reduces mucus secretion
better O2 uptake

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3
Q

sym. action on CV system

A

increase HR, electrical impulse conduction, contractions
vasoconstriction of skin, some blood vessels
vasodilation in skeletal muscle

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4
Q

sym. action on Digestion

A

decreased salivation, secretions, motility

increased sphincter tone

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5
Q

sym. action on vision

A

pupil dilation

lens flattens

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6
Q

sym. action on energy mobilization

A

increased fatty acid release, glycogenolysis, glucagon release
Decreased insulin release
—> elevated blood glucose**

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7
Q

sym. action on brain activity

A

increased alertness, dilation of cerebral arteries

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8
Q

alpha adrenergic receptors enhance/constrict blood flow

A

constrict

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9
Q

beta adrenergic receptors enhance/constrict blood flow

A

enhance

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10
Q

adrenergic agent***

A

drug that mimics or enhances the actions of endogenous catecholamines EP or NE. Can be direct (activate adrenergic receptors) or indirect-acting (i.e. by inhibiting things that breakdown EP or NE or disrupting metabolism or elimination of NT. have no direct receptor actions)

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11
Q

adrenolytic agent**

A

drug that blocks (attenuates) actions of EP/NE

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12
Q

adrenoceptor blocker

A

adrengergic receptor antagonist (rarely used)

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13
Q

adrenergic neuron blocker

A

have non-receptor actions

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14
Q

primary way EP/NE’s actions are terminated

A

active reuptake either back into the nerve that released it, or by surrounding cell that can capture and take it up

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15
Q

does cocaine cross BBB?

A

yes

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16
Q

name 2 catecholamines

A

EP and NE

17
Q

T/F: EP/NE and the adrenergic receptors that mediate their actions are both in CNS and ANS

A

T

18
Q

2 broad families of adrenergic receptors

A

alpha and beta

19
Q

NE more/less potent on alpha receptors than beta receptors

A

more

20
Q

dopamine stimulates what type of receptors?

A

beta-1 receptors

21
Q

EP preferentially stimulates what type of receptors?

A

Beta-1 and 2. Also stimulates alpha-1 and 2

22
Q

Where are alpha-1,2 receptors located?

A

CNS, visceral organs