CH4 VOLATILE ANESTHETICS Flashcards by jenyvieve dela rosa

Q

Highest MAC for neonates 3.3%
6-12 months infants 3.2%
6-12 months infants 2.5

A

SEVOFLURANE

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Q

HIGHEST MAC during infants 1-6 months

A

ALL VOLATILE GAS EXCEPT Sevoflurane

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Q

VOLATILE anesthetics
_____ Tv
_____ rr

A

DECREASE TV

INCREASE RR

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Q

less waste to into the OR
hypoxic mixture
rebreathing of expired gas
more rapid depletion of c02 absorbent

A

LOW FLOW ANETHESIA

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Q

c02
methane
n20

A

green house gases

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Q

low blood/gass coef (0.42)
airway irritant ( coughing, breath holding / laryngospasm)
pungent

inc conc > inc heart rate and bp

A

DESFLURANE

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Q

blood/gas partition coefficient :

sevoflurane

A

0.65

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Q

blood/gas partition coefficient :

N2O

A

0.46

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Q

blood/gas partition coefficient :

desflurane

A

0.42

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Q

blood/gas partition coefficient :

isoflurane

A

1.5

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Q

blood/gas partition coefficient :

enflurane

A

1.9

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Q

blood/gas partition coefficient :

halothane

A

2.5

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Q

SAME VAPOR PRESSURE ?

can interchange

A

HI
halo 243
iso 238

SEEN
SEVO 160
enflurane 172

des 665

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Q

Filling a vaporizer with an agent whose vapor pressure is higher result to a _____ concentration

A

HIGHER

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Q

Filling a vaporizer with an agent whose vapor pressure is lower result to a _____ concentration

A

LOWER

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Q

does not alter arterial blood pressure , SV ,SVR, baroreceotor reflex

increases HR
mild inc CO

dose dependent direct myocardial depressant due to symphathetic activation

A

N2O

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Q

causes DEC IN SVR

A

DIS

DESFLURANE
ISOFLURANE
SEVOFLURANE

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Q

causes direct myocardial contractility

A

HE

HALOTHANE
ENFLURANE

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Q

Dec CO

A

HALOTHANE

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Q

MAINTAIN CO

A

DIS
DESFLURANE
ISOFLURANE
SEVOFLURANE

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Q

INC CO

A

N20

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Q

ANTIGEN INDUCED bronchospasm
not reduce cardiac ouput
dec SV, MAP, SVR
inc HR ( baroreceptor)

A

ISOFLURANE

Q

inc blood pressure and HR( inc conc rapidly)
airway irritation
sympathetic response

A

DESFLURANE

Q

lowest solubility constant

A

DESFLURANE

0.42

Q

highest blood gas solubility

A

HALOTHAN 2.5

ISOFLURANE 1.5

Q

low gas/blood solubility

gases more in the _____

A

ALVEOLI

Q

high gas/blood solubility

gases more in the _____

A

BLOOD

Q

rate of uptake is influenced by ?

A

CO
blood /gas solubility coefficient
alveolar to venous partial pressure difference

Q

lower CO

A

inc FA/F1

Q

vessel rich group?

A

75% CO
10 % TBW 
BRAIN
HEART
SPLEEN 
LIVER
SPLENIC BED 
KIDNEYS
ENDOCRINE GLAND

Q

high vapor pressure 654mmHg

A

DESFLURANE

Q

a gradient of _____mmhg between PaC02 and EtCO2

A

2-5mmHg

Q

ETcO2 decrease by:

A

in MV 
HYPOTHERMIA
PULMO EMBOLISM 
SEVERE HYPOTENSION 
LOW CO
CARDIAC ARREST

Q

ETcO2 increase by:

A

HYPOVENTILATION 
REBREATHING OF EXHALED GASES 
INCREASED ABSORPTION CO2 ( lap)
MH
SEPSIS

Q

DOES NOT REDUCE CO

OR CARDIAC INDEX

A

DIS
DESLFURANE
ISOFLURANE
SEVOFLURANR

Q

For poorly soluble anesthetics such as n2O , transpulmonary shunting only slightly _______ rate of rise in the Fa/Fi

A

accelerates

Q

Gases with presrvatives?

A

HALOTHANE - thymol

methoxyflurane

Q

VRG reached steady state ina bout?

A

12 minutes

Q

which gas is soluble to plastic?

A

METHOXYFULRANE

ISOFLURANE and Halothane soluble plastic and rubber lesser extent

DIN- no solubke

Q

Inc concentration of COMPOUND A

A

Fresf absorbent
sola lime or baralyne 
high absorb temp
high con of sevo
closed circuit 
low flow anesthesia

Q

Calcium hydroxide
ambsorb

does produce compound A?

A

NOOO

it dows not have naOH and KOH

Q

percent of recovered metabolite

A

sevo 2-5%
iso 0.2%
des 0.02 %
methoxy 50 %

Q

Wash un filling circuit ? litter?

A

7L

bag 3l
hise 2l
absorbent 2”

Q

which gas?

Heart rate 1l- dec
SVR- no change
Cardiac Index- dec

A

HALOTHANE

Q

which gas?

Heart rate - dec
SVR- dec
Cardiac Index- dec

all dec

A

SEVOFLURANE

Q

which gas?

Heart rate - inc
SVR- dec
Cardiac Index- no change slig unc

A

ISOFLURANE

Q

which gas?

Heart rate 1m- inc
SVR- dec
Cardiac Index- dec

A

DESFLURANE

Q

ISOFLURANE

A

dec svr
inc hr
maintain co

Q

context 1/2 gases

1hr

A

1hr anesthestic
95 reduction

des 5 minutes ( 0.45)
sevo 18 minutes (0.65)
iso 30 minutes (1.64)

Q

how to compute for brain time constant

A

brain/ blood part coefficient x2

Q

time constant of volatile ?

A

1 min - 63 %
2min - 84%
3 min - 95%

3xtime constant=95 %

Q

What the effect of the following on your FI?

inc FGF
dec VC

A

INCREASED Fi

colllapse bag

Q

What the effect of the following on your FI?

inc FGF
dec VC

A

inc FI