CH10 ANATOMY, REGIONAL ANESTHESIA, and PAIN MANAGEMENT Flashcards
phenomenom associated with repeated injection of LA leading to decreased effectiveness
TACHYPHYLAXIS
Tachyphylaxis is most closely related to
DOSING INTERVAL
dosing interval is short no tachyphylaxis
if the dosing interval is longer TACHYPHYLAXIS DEVELOPS
Treatment for pruritis from neuraxial opiates
Nalbuphine 5mg iv
diphenhydramine 50mg iv
propofol 10mg iv
dexmedetomidine 30mcg iv -
will dec narcotic dose but not treat pruritus
MAXIMUM dose of lidocaine containing 1:200,000 epinephrine is
5mg/kg withou epi
7mg/kg with epi
1:200,000
5mcg/ml
1:200,000 = 1g/200,000ml
DIGITALIS TOXICITY?
loss of appetite nausea and vomiting pain in trigeminal neuralgia pain anf discomfort in the feet pain and discomfort in the extremities transient visual disturbance
earliest sign of lidocaine toxicity
5-10 Light headedness dizziness numbness tomgue perioral numbness tinnitus
10-15
seizure
unconsciousness
15-25
rspi depression
coma
> 25
cardio
site of opiates in the spinal cord
SUBSTANTIA GELATINOSA of SC
epidural mg of morphine equivalent to intrathecal
5mg epidural Mso4= 0.1-0.3mg in intrathecal dose
AMINO ESTERS LA
one I only
procaine
chloroprocaine
tetracaine
plasma clearance by pseudocholinesterase
short half lives
AMINO AMIDE LA
2 i
bupivacaine ropivacaine lidocaine mepicavaine prilocaine
hepatic clearance
longer half lives
Interscalene Block
hand and forearm surgery
C8-T1
ULNAR NERVE SPARING
PHRENIC NERVE 100%
HORNER SYNDROME blockade of stellate ganglion. 70-90%
LOW RISK OF PNEUMOTHORAX
Structures thatare transversed bu a needle placed in the midline prior to the epidural space?
skin subq supraspinous lig intserspinous lig LIGAMENTUM FLAVUM - snap
CAUDA EQUINA SYNDROME
symptoms?
secondary to?
Low back pain
bilateral lower extremity weakness
saddle anesthesia
loss of bowel and bladder control
POOLING of LA dependent area of the Subatachnoid space
CAUDA EQUINA SYNDROME
associated with
larger cathyer
lidocaine
tetracaine
lithotomy
DIFFERENTIAL NERVE BLOCK
Symphathetic berve block 2-5 higher than motor
sensory block 2-3 higher than motor block
in epidural :
sensory and symphatetic at the same area
pain persiating for more than 3 months after resolution of herpes zoster rash
PHN
POSTHERPETIC NEURALGIA
tx: TCA anticonvulsant opioids topical LA CAPSAICIN TENS
innervates the short extensors. of the toes and the skin of the web space between the great and second toes
deep peroneal nerve
block at the ankle by infiltration between the tensons of the ant tibial and extensor hallicis longus muscle
moat cardiotoxic LA
most to least
bupivacaine
ropivacaine
lidocaine
define: anesthesia dolorosa neuropathic pain dyaesthesia hyperalgesia allodynia
anesthesia dolorosa spontaneous pain in the are with anesthesia
neuropathic pain primary lesion or dysfunction in the nervous system
dyaesthesia unpleasant abnormal sensatiin
hyperalgesia increased response to normally painful stimulus
allodynia pain with stimulus that does not normally cause pain
most toxic ester LA
tetracaine
difference between CRPS TYPE 1 and 2
CPRS TYPE 1- trauma
CPRS TYPE 2 - nerve injury
the potency of local anesthetic is directly proportional to
LIPID SOLUBILITY
speed and onset is related to PKA
LOW PKA - inc about of non ionized and penetrate lipid portio fast
most important determinants of sensory level ?
BARICITY
AND POSITION of the pt
LOWEST CONC in the fetus relative to maternal serum
CHLOROPROCAINE
rapidly metabolized by paudocholinesterase
t1/2 45 seconds
HIGH SPINAL ANESTHESIA
hypotension sympathetic blockade venodilation(dec preload) arterial dilation( dec afterload) brady ( cardioaccelerator fibers T1-T4 )
PHANTOM LIMB
80% after amputation
incidence increased with PROXIMAL
few days after sx
PNB decreased incidence
treatment:
opioids
antidepressants
gabapentin
IVRA
BIER BLOCK
upper extremety
raised arm bandage tourniquet 250-300mmHg (2.5 the pt systolic) inject 40-45 mins tourniquest time deflate for 5 sec ( look for toxicity signs)
lidocaine 0.5% 1.5 to 3mg/kg
Largest intervertebral space
L5-S1
SNS originated in the thoracic and lumbar spinal cord ?
T1-Lcan cause total sympathetic block
DURAL SAC ENDS
s1 upt to s2
spinal cord ends at
adult l1-L2
infant L3
4 stages of epidural abscess
1st - localized back pain
2nd - nerve root or radicular pain
3rd- motor or sensory deficit
4th pareplegia
entrapment of lateral femoral cutaneous nerve as it courses below the inguinal ligaments
MERALGIA PAREsthesia
associated
burnjng pain over rhe lateral aspect of the thigh
not a complication of epidura
COMPLEX REGIONAL PAIN SYNDROME
burning continous pain
not anatomically distributes
cool red clammy skin HAIR LOSS associated atrophy and oateoporosis
NEUROLYTIC BLACKADE DIFFERENCE BETWEEN PHENOL AND ALCOHOL
phenol :
painless
dual action la and neurolytic agents
how luch LA SHOULD be administered by spinal segment
1-2mlsegment
(20-40 years old
elderly and preg
0.75-1.5ml/ segment
spread of LA ANESTHETICS PER EPIDURAL ___ secondary to___
2/3 spread cephalad
1/3 spread caudally
until level of T4
secondary to
INTRATHORACIC NEGATIVE PRESSURE
Artery of Adamkiewicz arises fromt he aorta at which spinal level
radicularis magna
T9-T12
ASA( anterior spinal artery ) - anterior 2/3 SC
posterior 1/3 SC - posterior Spinal artery
damage to this artery can lead to ischemia for the lower 2/3 SC. an cause paraplegia
artery of adamkiewicz