Ch.4 Epithelial Tissue (4.4) Flashcards
Epithelia Tissue or epithelium
consists of cells arranged in sheets in either single of multiple layers
ET may be classified in 2 general types:
- Surface Epithelium (covering and lining epithelium) - forms the outer covering of the skin; some internal organs; the inner lining of structures (such as blood vessels, ducts, body cavities) and the lining of the respiratory, digestive, urinary, and genital systems.
- Glandular Epithelium - makes up the secreting portion of glands (such as the thyroid gland, suprarenal (adrenal) glands, sweat glands, and digestive glands
Functional ET:
Protects, secretes (mucus, hormones, enzymes), absorbs (nutrients in the digestive canal), and excretes (various substances in the urinary tract)
An epithelial cell has an Apical surface
most superficial layer; a tubular duct that receives cell secretions; may contain cilia or microvilli
An epithelial cell has a Basal surface
deepest layer; adhere to extracellular material such as the basement membrane; hemidesmosomes are on this layer
A epithelia cell has a Lateral surface
may contain tight junctions, adhering junctions, desmosomes, and/or gap junctions
Basement membrane
a thin extracellular layer that consists of 2 layers: basal lamina and reticular lamina
- they have a role in kidney failure and blindness due to thickened blood capillaries
Basement membrane (basal lamina)
(top) closest to and secreted by the epithelial cells; contains the proteins lamina and collagen and glycoproteins and proteoglycans
Basement membrane (reticular lamina)
(bottom) closer to the underlying CT; contains collagen produced by CT cells fibroblasts
ET has its own nerve supply, but is avascular
it relies on the blood vessels of CT; the exchange of materials between the epithelium and adjacent CT is done by diffusion
ET has a high capacity for renewal due to high rates of mitosis. This is because:
ET is repeatedly exposed to physical stress and injury
Classification of Surface Epithelium (Layers)
- Simple epithelium (one layer)
- Pseudostratified epithelium (one layer that appears as several)
- Stratified epithelium (several layers)
Classification of Surface Epithelium (Cell Shapes)
- Squamous cells (thin, wide, flat)
- Cuboidal cells (cube-like)
- Columnar (rectangular)
- Transitional cells (change shape; variable)
Different types of ET
Simple Epithelium A. Simple squamous epithelium 1. Endothelium 2. Mesothelium B. Simple cuboidal epithelium C. Simple columnar epithelium 1.Ciliated 2. Nonciliated D. Pseudostratified columnar epithelium 1. Ciliated 2. Nonciliated
Stratified Epithelium A. Stratified squamous epithelium 1. Keratinized 2. Nonkeratinized B. Stratified cuboidal epithelium C. Stratified columnar epithelium D. Transitional or urothelium epithelium (lines most of the urinary tract)