ch3 Flashcards

1
Q

how is ATP replenished by ADP

A

ADP is phosphorylated to re-form ATP in an endergonic, or energy-requiring reaction.

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2
Q

3 major energy systems

A
  • creatine phosphate
  • anaerobic glycolysis
  • oxidative phosphorylation
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3
Q

predominant energy system in high intensity short-term exercise

A

creatine phosphate

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4
Q

predominant energy system in 400m race

A

anaerobic glycolysis

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5
Q

predominant energy system in a marathon

A

oxidative phosphorylation

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6
Q

How is creatine rephosphorylated after its use in skeletal muscle

A

with an ATP from the mitochondria (via creatine shuttle) reaches with creatine molecule to replenish the creatine phosphate

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7
Q

Provide some examples of exercises or the types of training that creatine supplementation would be useful for

A

high-intensity/short duration
- strength and power training
- sprinting & explosive mvts
- HIIT
- combat sports
- body building

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8
Q

suggested creatine supplement regimen

A

acute: 20-25g/day 5-6days
maintain: 2-3g/day
slower inc: 3g/day

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9
Q

effectiveness of creatine supplementation

A

30% non-responders

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10
Q

Is glucose in the muscle available for the regulation of blood glucose

A

no
This is because muscle cells lack the enzyme glucose-6-phosphatase, which is required to convert glucose-6-phosphate (G6P) into free glucose that can be released into the bloodstream.

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11
Q

what is glycolysis

A

breakdown of glucose through a specific series of chemical steps to phosphorylate ADP and from ATP

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12
Q

what is glycogenolysis

A

breakdown of glycogen for energy

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13
Q

wha is a rate limiting enzyme

A

enzyme that controls the speed of all the rx in the same way that the overall speed of an assembly lline is governed by the speed of the slowest worker

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14
Q

rate limitin enzyme for glycolysis

A

phosphofructokinase (PFK)

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15
Q

net ATP production of anaerobic glycolysis

A

2

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16
Q

glycolysis vs glycogenolysis (ATP)

A

when breaking down strating form glycolysis = 2ATP
glycogenolysis = 3ATP

17
Q

what impacts the anaerobic glycolysis more

A

PFK activity
rarely limited by depletion

18
Q

major disadvantage of anerobic glycolysis

A

build up of acidity

19
Q

metabolic acidosis

A

build up of acidity from anaerobic glycolysis
causes fatigue
anaerobic can only last 1-2 min bc of it

20
Q

How is lactate that is produced as a result of anaerobic glycolysis disposed of or used in the body?

A

accumulation of lactate does inc acidity but it is not only a waste product
lactate can be turned into pyruvate to be used as energy after

21
Q

. What is the predominant energy system during moderate-intensity, long-term exercise?

A

oxidative phosphorylation

22
Q

What is meant by the term V˙O2max?

A

is the maximum amount of oxygen that an individual can utilize during intense or maximal exercise. It is a key indicator of aerobic fitness and cardiovascular endurance.

23
Q

When aerobic exercise begins, why does it take a few minutes for oxygen consumption to rise to a level that will supply sufficient energy to support the exercise?

A

aerobic lag time
HR, SV and respiratory rate need time to adapt and inc to reach steady state
oxygen delivering is limited bc blood flow not yet ajusted

24
Q

whaere does energy come from in the adaptation phase in the begining of aerobic activity

A

from the anaerobic systems until the body has adapted to its oxygen needs

25
. What are the phases of oxidative phosphorylation?
1. carbs, fats, prot prepared to be metabolized aerobically 2. krebs cycle (oxidize) 3.electron transport chain rel energy to rephosphorylate ADP to ATP * all in mitochondria
26
How does quantity and timing of the ATP produced with oxidative phosphorylation compare to that produced from glycolysis?
oxidative = long + more energy glycolysis = fast, less ATP
27
Why does oxygen consumption remain elevated for a period of time after exercise?
EPOC (excess postexercise oxygen consumptiion) oxygen still high to replenish creatine phosphate via creatine shuttl ein mitochondria (needs oxygen to reattach phosphate to creatine) also lactate taken up by aerobic tissue to be converted to pyruvate and metabolised aerobically in mitochndria
28
Why are proteins not a preferred fuel source when compared to carbohydrates and fats?
breakdown of protein metabolically taxing compared to carbs and fats
29
advantage carbs for high intensity exercise
Fewer chemical steps are involved in carbohydrate oxi- dation, and less oxygen consumption is required for the amount of ATP produced, making carbohydrates the pre- ferred fuel source at higher intensities of exercise.