Ch18 - Adrenergic Drugs Flashcards
Adrenergics are part of what CNS system?
Autonomic nervous system, sympathetic
Sympathetic system practices what kind of responses?
Fight/Flight
What kind of neurotransmitters do adrenergic receptors respond to?
Catecholamines: norepinephrine and epinephrine
Where are the alpha 1 receptors located?
Located on the post synaptic nerve
Where are the alpha 2 receptors located?
Located on pre synaptic cells
Tissue, muscle,organs, that the nerve stimulates
They control the release of neurotransmitters
Where are the beta 1 receptors located?
Post synaptic cells
Primarily in the heart
Where are the beta 2 receptors located?
Post synaptic cells
Primarily in smooth muscle, bronchioles, arterioles, visceral organs
What effects to beta 1 receptors have on the body?
Increase contraction
Increase heart rate
Increase conduction
Increase renin secretion
What effects do beta 2 receptors have on the body?
Bronchodilation
Decrease gi motility, decrease secretions, vasodilation( decrease b/p) , increase blood sugar
What do the dopaminergic receptors do to the body?
They only respond to catecholamine dopamine
Increase blood flow to brain, kidneys, viscera
Cholinergics are part of what CNS system?
Autonomic nervous system, Paraympathetic
Parasympathetic nervous system practices what kind of responses?
Rest/digest
What kind of neurotransmitters respond to cholinergic receptors?
Acetylcholine
What effects do muscarinic receptors have on the body?
Increase gi and bladder motility, increase secretions, constricts pupils, bronchoconstriction, decrease heart rate, contraction, and conduction
If a drug is blocking activation of a receptor it is called?
Antagonist
If a drug is activating a receptors binding it is called?
Agonist