Ch 12 - Depressants And Muscular Relaxants

Question 1

Sedatives have what kind of effect?

Answer 1

Reduce nervousness, excitability, and irritability without causing sleep

Question 2

Hypnotics have what effect on the body?

Answer 2

Cause sleep and have more effect on CNS than sedatives

Question 3

What is the most commonly prescribed sedative/hypnotic?

Answer 3

Benzodiazepine

Question 4

Name the 3 type of drugs used for sedatives and hypnotics?

Answer 4

Barbiturates, benzodiazepines, non benzo (miscellaneous)

Question 5

What are the enzymes in the brain for benzodiazepines called?

Answer 5

Gamma aminobutyric acid (GABA)

Question 6

What does the enzyme GABA do?

Answer 6

Prevent overstimulation in the brain

Question 7

What are some adverse effects of sedatives and hypnotics?

Answer 7

Cannot mix with herbal supplements kava/valerian, grapefruit, alcohol

Question 8

What is the main problem when using barbiturates?

Answer 8

Deprivation of sleep by interruption of REM cycle

Question 9

Barbiturates affect metabolism how?

Answer 9

Activating cytochrome p40 speeding up metabolism of other drugs

Question 10

A woman taking an oral contraceptive should be cautious while taking a barbiturate why?

Answer 10

The barbiturate activates cytochrome p40 speeding up metabolism of oral contraceptive allowing it not to work properly

Question 11

What is the name of a commune muscle relaxant?

Answer 11

Dantrolene

Question 12

What should you look for as a nurse after giving someone a muscle relaxant?

Answer 12

Muscle weakness, lightheadedness, somulance

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