CH1 highlighted notes

Question 1

Ig with the lightest MW of 150,000

Answer 1

IgG

Question 2

Ig that can move through a placenta

Answer 2

IgG

Question 3

Ig that can also be in a pentamer form

Answer 3

IgM

Question 4

Ig with the highest MW of 900,000

Answer 4

IgM

Question 5

___ chain is where ea. molec is double bonded together in a Ig

Answer 5

J-chain

Question 6

primary immune response is with what Ig

Answer 6

IgM

Question 7

secondary immune response is done with the ___ Ig

Answer 7

IgG

Question 8

Fetus recieves a mothers ___Ig

Answer 8

IgG

Question 9

Fetus maily produce ___Ig and a little bit of __&___

Answer 9

mainly: IgM

Small amt: IgG and & IgA

Question 10

Ig with the main fxn of secretions

Answer 10

IgA

Question 11

Ig with the main fxn of acting during an allergic rxn

Answer 11

IgE

Question 12

3 fxn of Ig

Answer 12

neutralize
kill (w/ presents of complement)
Opsonize (IgG and IgM activate C3b

Question 13

IgG and IgM activate Complement tp produce ____ for opsonin

Answer 13

C3b

Question 14

A-antigen in ABO has ___

Answer 14

N-acetylgalactosamine

Question 15

B-Antigen in ABO has ___

Answer 15

galactose

Question 16

plasma contains antibodies ____ against the missed antigen in blood

Answer 16

IgM

Question 17

agglutinogen aka ___

Answer 17

antigen

Question 18

agglutinin aka ___

Answer 18

antibody

Question 19

_____: agglutination occurs if Ab in serum against antigen in RBC

Answer 19

coomb’s test

Question 20

Moter’s anti-D antibody ____ passes to the second Rh(D)+ fetus= erytroblastic fetalis

Answer 20

IgG

Question 21

NKC is activated by ___ produced by macrophages

Answer 21

IL-12

Question 22

NKC is activated by ___ produced by virus-infected cells

Answer 22

alpha & beta interferon

Question 23

___ : glycoproteins inhibit viral protein syn. (degrade viral mRNA - not host mRNA)

Answer 23

interferons

Question 24

___ inferferon is produced by leukocytes

Answer 24

alpha

Question 25

___ inferferon is produced by fibroblast

Answer 25

Beta

beta= fiBroBlast

Question 26

___ interferon is produced by lymphocyte T-cells

Answer 26

gamma

Question 27

_____: protein that helps other components of the immune system

Answer 27

complement

Question 28

cytokine IL-__ activates helper T cells & fever

Answer 28

IL-1

Question 29

cytokine ____ stimulates neutrophils for adhesion and inhibits lipoprtein lipase

Answer 29

TNF

Question 30

complement ____ attracts chemotaxic mediators to a fb

Answer 30

C5a

Question 31

O2 dependent mechanism for phagocytosis causes ____ death of the cell

Answer 31

apoptosis

Question 32

O2 independent mechanism for phagocytosis causes ___ death of the cell

Answer 32

phagolysosome

Question 33

origin and maturation site of T cells

Answer 33

origin: Bone marrow

Maturation : thymus

Question 34

origin and maturation site of B cells

Answer 34

Origin & maturation: bone marrow

Question 35

The cell ssurface of a T cell has ___

Answer 35

CD3

Question 36

cell surface of a B cel has __ & __

Answer 36

IgM (monomer) and IgD

Question 37

CD4 fxn= ____

Answer 37

helper

Question 38

CD8 fxn = ____

Answer 38

cytotoxic

Question 39

CD3 fxn = ____

Answer 39

transmitter

• transmits info from CD8 to CD4

Question 40

CD4 recognizes antigens ass with class ___ protein

Answer 40

Class II MHC

Question 41

____ helps B-lymphocytes to produce Ig

Answer 41

helper CD4

Question 42

___ helps CD8 lymphotcytes to become activated cytotoxic T cells

Answer 42

helper CD4

Question 43

CD___ suppresses Ig production

CD___ activates Ig Production

Answer 43

CD8: suppress
CD4: activates

Question 44

CD8 bind to class ___ protin

Answer 44

class I-MHC

Question 45

antigen binds to class II MHC –> CD___ recognizes it and produces IL-__ –> CD__ is stim–> produces ___

Answer 45

CD4 recognizes antigen produces IL-2 –> CD8 is stim and produces perforin