Ch 1 Flashcards
Innate humoral Immunity: ____
neutrophils
Adaptive Humoral Immunity: _____
B cell antibodies
Innate Cell mediated immunity:______
macrophages
Adaptive Cell-mediated Immunity :______
Helper T cells cytotoxic T cells
Neutrophil and B cells are ___ immunity
humoral
Macrophages and Helper T cells are _____immunity
Cell- mediated
B cell antibodies are made from ___
plasma
Innate immunity is ___ specific
non-specific
adaptive immunity is ___ specific
highly specific
Helper T (CD4) cells release ___ protein to activate helper cells and macrophages
IL-2
T cell cytotoxic CD8 release ___ protein to activate cytotoxic cells
IL-2
T cells mediate type ___ hypersensitivity
Type IV allergies
class II MHC activates CD__
CD4
Class I MHC activates CD__
CD8
Normal ratio of CD4:CD8 =
3: 2
cc: reversed will lead to AIDs and other opportunistic infections
all T cells have CD__
Its fxn: ____
all T cells have CD3
its fxn: transmit info that the T cell receptor sends from outside to inside
Origin of T cells:___
Maturation of T cells___
Origin: Bone marrow
Maturation: thymus
Origin of B cells : ____
Maturation of B cells _____
Bone Marrow
bone marrow
B cells carry which (2) Ig?
IgM & IgD
(2) mediators of active immunity
antibody and T cells
(1) mediator of passive immuity
atibody only
active immunity has antibody and t cells
Memory cells have Ig___ that serve as antigen receptor for reexposure to the same antigen
IgG
(2) protein hormones produced by Macrophages
IL-1- activates helper T cells & pyrogen
TNF: stim neutrophils for adhesion, necrosis of Tumor cells
(3) protein hormones produced by Helper T cells
IL-2: stim helper T cells and cytotoxic cells to grow
IL4: promotes growth of B cells
IL-5: Stim differentiation of B cells
____: foreign sub., when it is intro to the bd. it produces an immune response
antigen
___: sites on antigen molec. that can rxn with the antibody
epitopes
