Ch02 Flashcards

1
Q

A resting neuron is ______

A

polarized.

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2
Q

What does a cell being polarized mean?

A

difference in electrical charge between the inside and the outside of the cell.

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3
Q

Ions are?

A

electrically charged molecules

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4
Q

What charge do anions have?

A

negative

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5
Q

What charge to cations have?

A

positive

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6
Q

What is the ion channel?

A

proteins that span the membrane and can allow selective ions to pass through

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7
Q

What does it mean if a channel is gated?

A

it opens and closes in response to signals

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8
Q

What does it mean if an ion shows selective permeability?

A

Allows K+ but not Na+ to enter and leave the cell freely

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9
Q

What two opposing forces drive ion movement

A

Diffusion
Electrostatic pressure

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10
Q

Diffusion causes ions to?

A

spread towards a uniform concentration along a concentration gradient

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11
Q

Electrostatic pressure causes ions to flow towards?

A

oppositely charged areas

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12
Q

What is the equilibrium potential

A

the electrical charge that balances two opposing forces- the concentration gradient and electrostatic pressure and corresponds to the resting potential.

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13
Q

Depolarization is a

A

decrease in membrane potential- the interior of the cell becomes less negative and closer to zero.

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14
Q

Hyperpolarization is an

A

increase in membrane potential- the interior of the cell becomes even more negative and farther from zero

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15
Q

Relative stimulus strength is?

A

the information being encoded in changes in the number of APs produced

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16
Q

Afterpotentials

A

small changes in membrane potential after action potentials

17
Q

What are action potentials produced by?

A

the sudden rush of Na+ ions

18
Q

What happens during the absolute refractory phase?

A

no action potentials can be produced?

19
Q

What happens during the relative refractory phase?

A

only very strong stimulation can produce and action potential.

20
Q

What is myelin?

A

A sheath of insulation around the axon, formed by glial cells, which speeds conduction.

21
Q

what is the Node of ranvier

A

a small gap in the insulating myelin sheath

22
Q

What is saltatory conduction

A

the potential traveling inside the axon ‘jumps’ from node to node

23
Q

What happens when an action potential reaches the axon terminal

A

it causes the release of a neurotransmitter into the synapse

24
Q

Postsynaptic potentials are

A

brief changes in the postsynaptic membrane potential of the cell in response to a neurotransmitter.

25
Excitatory postsynaptic potential (EPSP)
a small local depolarizing potential in the postsynaptic membrane that pushes the cell closer to the action potential threshold, increasing the likelihood that the neuron will fire an action potential.
26
Inhibitory postsynaptic potential (IPSP)
a hyperpolarizing potential in the postsynaptic membrane that pushes the cell further away from threshold, decreasing likelihood of neuron firing and action potential.
27
When do inhibitory postsynaptic potential (IPSPs) results?
when chloride ions (Cl-) rush into the cell, making the inside more negative
28
What is the sequence of neurotransmission:
1. Action potential arrives at the presynaptic axon terminal 2. Voltage gated calcium (Ca2+) channels in the terminal membrane open, and Ca2+ ions enter 3. Ca2+ ions cause synaptic vesicles filled with neurotransmitter to fuse with the presynaptic membrane, releasing transmitter into the synaptic cleft 4, Transmitters bind to postsynaptic receptor molecules, causing ion channels to open and leading to an EPSP or IPSP 5. EPSPs or IPSPs spread toward the postsyanptic axon hillock- if threshold is reached, an action potential will occur 6. Synaptic transmission is rapidly stopped 7. Transmitter may activate the presynaptic receptors that decrease transmitter release.
29
What are ligands?
molecules that fit into receptors and activate or block them
30
Neurotransmitter action is brief and is halted by?
Degradation: the rapid breakdown and inactivation of transmitter by an enzyme Acetylcholinesterase (AChe) Reuptake: transmitter is cleared from the synapse by being absorbed back into the presynaptic axon terminal through transporters.
31
What is spatial summation
the summing of all the potentials that reach the axon hillock from locations across the cell body. If the overall depolarization- the sum of EPSPs(+) and IPSPs(-) reaches or exceeds the threshold, an AP is produced
32
Temporal summation is the?
summing of all the potentials that reach the axon hillock based on time of arrival. The closer together in time the potentials arrive, the greater their impact and likelihood of producing an action potential.
33
An electroencephalogram (EEG) is a recording of?
spontaneous brain potentials
34
Event related potentials (ERPs) are EEG responses to a?
single stimulus, such as a flash of light or loud sounds.
35
Tonic clonic seizures
abnormal EEG activity throughout the brian
36
simple partial seizures
brain waves show patterns of seizure activity for 5 to 15 seconds, may occur several times a day
37
complex partial seizures
do not involve entire brain, often preceded by an unusual sensation, or AURA
38
Many seizure disorders can be controlled with what kind of medications?
antiepileptic medications
39
When medication does not work and seizures are severe and frequent, part of an awake patient's brain can be removed
neurosurgery