Ch 9: Cellular Respiration Flashcards
ATP
Consistes of 3 phosphate groups, ribose( 5C sugar), adenine
Adenine
Important in ATP, DNA, RNA
(Guanine= important in GTP, DNA, RNA)
(Thymine= important in TTP, DNA, RNA)
(Cytosine = important in CTP, DNA, RNA)
ATP hydrolyzed
Energy released
Producing ADP and inorganic phosphate, energy
Highly exergonic
Phosphorylation
Leads to shape change. Even small change can affect protein activity
Pellagra
Deficiency of niacin (vitamin b3, nicotinic acid)
Glycolysis
Occurs in cytosol
Uses 2 ATP
Comes out: 4 ATP (net production of 2 ATP), 2NADH, pyruvate
feedback inhibition
Presence of product inhibits enzyme 1
Type of allosteric inhibition
If electron acceptor (O2) present
Keeps cycle then to electron transport chain
If electron acceptor (O2) not present
Fermentation
Krebs cycle hypothesis
Pyruvate emerges mitochondria by means of special transport protein in membrane = active process
Uses ATP
Citrate (first thing pyruvate interacts with in krebs)
Most reduced
Oxaloacetate (last thing pyruvate interacts with in krebs)
Most oxidized
Coenzyme A
Transfers acetyl group to oxaloacetate
All 8 of Krebs cycle rxns occur
In mitochondrial matrix, outside cristae
Pyruvate dehydrogenase
B/w pyruvate and acetyl CoA
Large complex enzyme
Located at the inner mitochondrial membrane
Made up of 3 enzymes and 5 cofactors (thiamin, niacin, pantothenic acid)