Ch 4: Nucleic Acids

Question 1

Single change in amino acid sequence

Answer 1

Change in shape Is induced when blood is in a deoxygenated State.

Change structure and function of protein

Question 2

When deoxygenated

Answer 2

Protein takes on filamentous straight shape. Changes shape of cell

Question 3

Change in amino acid:

Answer 3

Makes hemoglobin hard for malarial parasite to digest and causes rupture of red blood cells before parasites are mature

Question 4

DNA is found…

Protein synthesis takes place…

Answer 4

Nucleus

Cytoplasm

Question 5

DNA characteristics

Answer 5

-alpha double helix
-these strands meet at precise pairings= bases
-outside strands= sugar deoxyribose and phosphate are backbone
- 5’- 3’ one strand and other strand 3’-5’
-

Question 6

Purines

Answer 6

Adenine and guanine

Question 7

Pyrimidines

Answer 7

Thymine and cytosine

Question 8

DNA has… while RNA has…

Answer 8

Thymine…. uracil

Question 9

Nitrogenous bases

Answer 9

Nitrogens in them tend to pick up protons in water = solution basic

Question 10

Deoxyribose

Answer 10

Lack of oxygen compared to ribose, increases stability of DNA as compared to RNA

Question 11

Nucleotide

Answer 11

1 phosphate group, 5-carbon sugar, nitrogenous base

Phosphate on 5’) (nitrogenous base on 1’

Question 12

Nucleoside

Answer 12

Base and sugar without phosphate group

Question 13

Addition of phosphate groups…

Answer 13

Raises the potential energy of monomer

Adenosine tri-phosphate = energy rich compound

Question 14

Joining two nucleotides

Answer 14

Phosphodiester bond

Ester= at least 1 OH group is replaced by an O alkyl group

Question 15

Where is phosphodiester linkage

Answer 15

3’ and 5’ carbons joined by ester linkage

Question 16

Chargaffs experiement

Answer 16

Total number of purines and pyrimidines are equal

#A = #T
#C = #G

Question 17

Wilkins and Franklin

Answer 17

X ray crystallography revealed repeaters scattered dimensions (.34, 2.0, 3.4)

Question 18

Watson-Crick

Answer 18

Complimentary base pairings

Question 19

Sick cell individuals

Answer 19

One base pair changed -> T where A should be and on other side an A where T should be