Ch. 8 - Geriatric Pharm Flashcards
Decreased Organ Function –>
- Monitor effect of drug therapy to prevent
- Risk of adverse reactions
- Possible drug toxicity
GI System (1):
Increase: PH gastric secretions
GI System (2):
Decreased:
- Peristalsis with delayed emptying time - Motility laxatives
Cardiac / Circulatory:
Decreased:
- cardiac output - Blood flow
Hepatic:
Decreased:
- enzyme function - Blood flow
Renal:
Decreased:
- blood flow - Functioning nephrons - Glomerular filtration Rate
Absorption (1):
- ) Slowed d/t: blood flow decrease
- ) Gi motility decrease
- ) Drugs remain in gi tract longer
Absorption (2):
Acidic drugs poorly absorbed d/t: -alkaline gastric secretion increase ------------------------------------------------------- Amount of dose absorbed -Not affected
Distribution (1):
Decreased protein binding sites for drugs:
- ) Increase amount of free drug in circulation
- ) Increase chance for adverse reaction
Distribution (2):
Loss of body water:
-decreased volume of distribution of water soluble drugs then drugs become more concentrated (not enough volume for drug to be distributed)
Distribution (3):
Total body fat increased:
-Fat-soluble drugs may be absorbed in fatty tissue and released slowly into bloodstream then decreases in desired drug affect
Metabolism (Biotransformation):
Decreased blood flow to liver:
- ) Decreased ability to metabolize and detoxify drugs
- ) Increased risk for drug toxicity
Excretion:
- ) Decreased cardiac output & blood flow throughout circulation
- ) Decreased renal functioning
- drug toxicity more likely
Pharmacodynamics:
- ) Lack of affinity to receptor sites throughout the body
2. ) May experience altered drug response
Barriers to Effective Medication Use (1):
Sensory losses:
- ) Difficulty reading labels
- ) Hearing loss
Barriers to Effective Medication Use (2):
Memory loss:
- ) Recent memory loss
- ) When to take meds
- ) Associate with daily activity
Polypharmacy (1):
Administration of many drugs together
Polypharmacy (2):
- ) Multiple health care providers
- ) Herbal therapy
- ) OTC drugs
- ) Discontinued Rx meds
Polypharmacy (3):
At risk for drug-drug interactions
Barriers to Effective Medication Use (3):
Financial loss:
- ) Decreased
- ) May not
Barriers to Effective Medication Use (4):
- ) Communication Problems
- ) Instructions
- ) English/ technical jargon
- ) Pride trust awe of profession
Assessment (1):
- ) Disabilities
- ) Sensory functioning
- ) Home environment
- ) Financial concerns
Assessment (2):
Is client able to open medication bottles
-Easy open caps
Implementation (1):
Oral meds:
- ) Position comfortably
- ) Liquid dosage available
- ) Don’t rush client
Implementation (2):
IM injections—Avoid:
- ) Deltoid muscle
- ) Vastus lateralis muscle (non- ambulatory pts)
Implementation (3):
IM injections—-Preferred:
- ) Dorsogluteal
- ) Ventrogluteal
Implementation (4):
IV administration:
-Watch flow rate to prevent circulatory overload
Health Teaching Older Clients (1):
- ) Glasses hearing aid
- ) Speak clearly slowly
- ) Short sessions 15-20 min
- ) Visual aids
Health Teaching Older Clients (2):
- ) Treat with respect
- ) Include family member/ support person
- ) Emphasize following Rx orders exactly
- ) Discard old expired meds
Evaluation:
- ) “Client sustains no injury from self-administration of medications”
- ) “Client is able to verbalize understanding of medication regimen”