ch 7 principles of pathophysiology Flashcards

1
Q

What is pathophysiology?

A

The study of how disease processes affect function of the body.

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2
Q

What is the purpose of the cell membrane?

A

To protect the cell, and also selectively allow substances in and out of the cell.

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3
Q

What do mitochondria do?

A

Convert glucose and nutrients into ATP.

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4
Q

How can the water levels inside and outside, affect a cell?

A

It could dehydrate the cell and interrupt cellular and electrical functions.

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5
Q

Supply of _____ must match the body’s glucose requirement.

A

Insulin.

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6
Q

What could occur during anaerobic metabolism?

A

The body may become too acidic.

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7
Q

Many diseases affect the ______ of the membrane.

A

permeability.

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8
Q

What are the key structures that affect homeostasis?

A

The hypothalamus and the medulla oblongata.

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9
Q

What occurs in the parasympathetic nervous system?

A

“Feed or breed” functions.

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10
Q

How does the parasympathetic nervous system affect the PR and BP?

A

It reduces them.

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11
Q

When does the sympathetic nervous system kick in?

A

“Fight or flight” situations.

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12
Q

What are the chemicals present in the sympathetic nervous system?

A

Epinephrine and norepinephrine.

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13
Q

How does the sympathetic nervous system affect the PR and BP?

A

It increases them.

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14
Q

Where are oxygen and carbon dioxide exchanged?

A

Between the air in the alveoli and the blood in the capillaries.

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15
Q

What is tidal volume?

A

The volume of air moving in and out during each breath cycle.

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16
Q

What is minute volume?

A

Amount of air moved in and out of the lungs within a minute.

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17
Q

How do you calculate minute volume?

A

Tidal volume x respiratory rate.

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18
Q

What are respirations controlled by?

A

The medulla oblongata.

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19
Q

How can the alveoli’s ability to exchange gases affect oxygen and carbon dioxide levels?

A

Can result in hypoxia and hypercapnia.

20
Q

What detects changes in oxygen and carbon dioxide levels?

A

Chemoreceptors.

21
Q

What is plasma oncotic pressure?

A

Proteins in plasma attract water, pull it away from cells and into the bloodstream.

22
Q

What is hydrostatic pressure?

A

Water is pissed out of blood vessels and toward cells.

23
Q

What are some common causes of excessive permeability?

A

Sepsis or high altitude.

24
Q

What is SVR?

A

Systemic vascular resistance, the pressure inside of blood vessels, and also known as hypertension.

25
Lack of sympathetic response can lead to _____.
Shock.
26
What is the average output (stoke volume) of blood per contraction of the heart?
70 mL.
27
What is preload?
The amount of blood returning to the heart.
28
What is contractility?
How hard the heart squeezes.
29
What is afterload?
Pressure the heart has to pump against, in order to force blood out into the system.
30
What is stoke volume (output) based on?
Preload, contractility, and afterload.
31
How is cardiac output calculated?
Stroke volume x beats per minute.
32
Hypoperfusion can result in ______.
Shock.
33
What is hypovolemic shock?
Low blood volume.
34
What is distributive shock?
Low blood vessel tone.
35
What is cardiogenic shock?
Heart fails to pump.
36
What is obstructive shock?
Blood cannot flow.
37
What are the signs of compensated shock?
Slight mental status change Increased PR Increased RR Delayed capillary refill Pale, cool, clammy skin Sweating
38
When does decompensated shock occur?
When compensating measure fail.
39
What is decompensated shock characterized by?
Decreased BP Altered mental status
40
What is irreversible shock?
Inadequately perfused organ systems begin to die, death commonly follows.
41
The body is ______ % water.
60.
42
How is the body's 60% water mass distributed?
Intracellular- 70% Intravascular- 5% Interstitial- 25%
43
What pulls fluid into the bloodstream?
Blood plasma proteins.
44
What is edema?
Swelling associated with the movement of water.
45
What is the shock-absorbing fluid that surrounds the brain and spinal cord called?
Cerebrospinal fluid.
46
______ secrete hormones.
Glands.
47
An allergic reaction can result in _____.
Edema.