Ch 7: Genetics and Evolution (Princeton Review) Flashcards
The Hardy-Weinberg law states that the __________ of alleles in the gene pool of a population will not ______ ____ ____, provided that the following assumptions are true:
- ) no mutation
- ) no migration
- ) no natural selection
- ) random mating
- ) the population is sufficiently large to prevent random drift in allele frequencies (genetic drift)
frequencies
change over time
p. 254
A population consists of members of a species that ____ ___ __________ with each other. Even if dispersed over the whole ocean like sea turtles, as long as they meet up and mate, they are a population.
mate and reproduce
p. 253
To a population geneticist, each individual is merely a temporary carrier of the _______ in a population. Alleles are examined across the entire population rather than in the individual. The sum total of all genetic information in a population is called the ____ ____.
alleles
gene pool
p. 253
For an autosomal gene in a population of 2,000 individuals, how many copies of the gene are present in the gene pool?
2 copies of the gene in each individual, so 4,000 copies total in the gene pool
p. 254
What Hardy-Weinberg means at the molecular level is that segregation of alleles, independent assortment, and recombination during meiosis can alter the combinations of alleles in gametes but cannot ________ or ________ the frequency of an allele in the gametes of one individual or the gametes of the population as a whole.
increase or decrease
p. 254
If 20% of the population is heterozygous for an allele Q and 10% is homozygous, what will be the frequency of the allele in the population?
0.5 x (20% heterozygotes)
+ 10% homozygotes
= 20%
p. 254
If you cross 100 homozygous green pea plants and 100 homozygous yellow pea plants, what will be the frequency of the yellow allele in the gene pool of the progeny?
50%, just as in the parental generation
And if the criteria for Hardy-Weinberg equilibrium are maintained, the frequency will still be 50% after 4 generations.
p. 254
If two genes are closely linked on the same chromosome, will Hardy-Weinberg still apply to these genes?
Yes, independent assortment is not a requirement for Hardy-Weinberg, as long as the 5 assumptions hold true.
p. 254
State the Hardy-Weinberg law mathematically.
p + q = 1
(p + q)2 = 12
p2 + 2pq + q2 = 1
p2 is the frequency of the GG genotype
2pq is the frequency of the Gg genotype
q2 is the frequency of the gg genotype
The expected unlinked phenotype ratio from a cross between two double heterozygotes is ______, with 9/16 of the offspring double-dominant, 3/16 dominant/recessive, 3/16 recessive/dominant, and 1/16 double-recessive.
9:3:3:1
(Review of Princeton Review practice exam 1)
Due to the extreme complexity of crossing over, meiotic ________ takes the most time in meiosis, days sometimes.
prophase
p. 232
In meiosis, during prophase I, homologous chromosomes align themselves with each other in synapsis, with the 2 copies of each gene on two different chromosomes brought closely together. These paired homologous chromosomes are called a ________ or ______.
bivalent or tetrad
p. 232
The difference between meiotic metaphase I and mitotic metaphase is….
…..the tetrads are aligned at the metaphase plate, whereas in mitosis, sister chromatids are aligned on the metaphase plate.
p. 234
Sometimes during anaphase I of meiosis, homologous chromosomes fail to separate, and sometimes during anaphase II, ______ ________ fail to separate. This is called __________.
sister chromatids
nondisjunction
p. 235
If nondisjunction occurs, and the homologous chromosomes do not separate in meiosis I, then one daughter cell from this division will have _ copies of this chromosome and the other cell will have none. In meiosis II, sister chromatids will separate, leaving 2 gametes with _ copies of the chromosome and 2 gametes with no copies of the chromosome.
4
2
p. 235