Ch. 6 Spleen Flashcards
Its the largest structure of the reticuloendothelial system
Spleen
It’s an intraperitoneal organ located within the left upper quadrant of the abdomen whose primary objective is to filter the peripheral blood
Spleen
The largest lymphatic organ of the body
spleen
The _______ plays an important role in defense against infection in children while in adults, it produces lymphocytes and monocytes
Spleen
The spleen is responsible for ____________ in the fetus
Erythropoiesis
At what week gestation does the spleen begin to develop?
5th
What is the role of the spleen in adults?
produce lymphocytes & monocytes
RBC production in adults is primarily performed by what?
bone marrow
The spleen’s hematopoietic function which can return in cases of severe anemia
extramedullary hematopoiesis
What specialized tissue is the spleen composed of?
white & red pulp
List the functions of the spleen
- Defense against disease
- Hematopoiesis/erythropoiesis
- Destruction and removal of flawed red blood cells and platelets
- Blood reservoir
- Storage of iron
Although red blood cell production in the adult is primarily performed by the bone marrow, the spleen hematopoietic function can return in cases of ______________.
Severe anemia
Specialized lymphatic tissue within the spleen
White pulp
Specialized tissue within the spleen that performs its phagocytic function
red pulp
A type of cell that Engulfs and destroys pathogens
Phagocytes
White pulp of the spleen does what?
produces and houses lymphocytes, carrying out the spleens lymphatic tissue
Red pulp of the spleen does what?
contains RBC’s and macrophages, performs the phagocytic function
The splenic process of removing irregular red blood cells from the bloodstream
culling
The splenic process of cleaning red blood cells of unwanted material
pitting
Doppler evaluation of the splenic artery normally demonstrates what kind of flow pattern?
low-resistance
What is the vascular anatomy of the spleen?
The splenic artery is a branch of the celiac trunk, which may be also referred to as the celiac artery or celiac axis. From the celiac trunk, the splenic artery courses laterally toward the spleen.
The ________ _______ can be confused for the main pancreatic duct in some patients because it takes a similar course in the body.
Splenic artery
What is the best patient position to best visualize the spleen?
Taking a deep breath with the patient lying on his or her right side
The splenic vein exits the spleen and travels along the posterior border of the pancreatic tail and body. It joins with the ______ posterior to the pancreatic neck to form the portal vein. Flow within the splenic vein will be toward the liver.
superior mesenteric vein
What is the normal sonographic appearance of the spleen?
Its frequently isoechoic to the liver, although it may be slightly more echogenic
a small, round island of splenic tissue often located near the splenic hilum or tail of pancreas
accessory spleen
This is also referred as a splenule, a splenunculus, or a supernumerary spleen
Accessory spleen
Where is the accessory spleen usually located?
near the hilum or possibly near the tail of the pancreas
The spleen may appear to be divided by a hyperechoic line in some individuals which is called..
Splenic cleft
What are the two uncommon congenital anomalies of the spleen?
Asplenia and polysplenia
Congenital absence of the spleen
asplenia
Development of multiple small masses of the splenic tissue
polysplenia
The implantation of ecotopic splenic tissue
Splenosis
The size of the spleen varies with ___ & ___.
age & sex (decreasing with advanced age)
Asplenia and polyslenia have been associated with
cardiac malformations & heterotaxia syndromes (organs in chest/abdomen are abnormally arranged)
Splenosis is a complication of
splenic trauma
A highly mobile spleen
wandering spleen
An individual with a wandering spleen could suffer from ___________ because of the vessels of the spleen may twist secondary to the hypermobility of the organ
Splenic torsion
The twisting of the splenic vasculature causing a disruption in the blood supply to the spleen and subsequent ischemia
splenic torsion
What is the most common abnormality of the spleen?
splenomegaly
the spleen should never measure more than ___ in length and ____ in thickness
12cm; 5cm
Reduction in the number of leukocytes in the blood
leukopenia