Ch. 6 Integumentary System (skin & related structures) Flashcards
Integumentary System
- composed of all 4 tissue types
- inlcudes hair, hooves, horns, & claws, as well as skin-related glands
- outer layer composed of dead cells
- <u>Keratinization</u> occurs as cells die
- protective and regulatory functions
General FUNCTIONS of Integumentary
- covers and protects underlying structures
- prevents desiccation
- assists in maintenance of body normal temperature
- excretes water, salt, and organic wastes
- sensory organ - relay tactile and pressure info to CNS
- vitamin D synthesis and nutrient storage
Integument = SKIN
-
2 layers
- <strong>Epidermis - </strong>keratinized stratified squamous epithelium
- <strong>Dermis </strong>(corium) <strong>-</strong> dense fibroelstic connective tissue
-
<strong>Hypodermis = </strong>subcutaneous layer/subcutis
- primarily adipose tissue for thermo-insulation and mechanical shock absorption
- pressure receptors = <u><strong>pacinian corpuscle</strong></u>
- allows skin to move freely over underlying muscle and bone without putting tension on the skin that would result in tearing
Epidermis (cells)
- <strong>Keratinocytes - </strong>majority of epidermal cells
- <strong>Melanocytes - </strong>produce melanin
- <strong>Langerhan’s cells - </strong>macrophages only found in epidermis
- <strong>Merkel cells - </strong>form Merkel disks
Keratinocytes
Majority of epidermis cells
- produce <strong><u>kertain</u></strong> = tought, fibrous, waterproof protein -> <strong>gives skin it’s resilicency and strength</strong>
Melanocytes
Produce <strong>melanin</strong><strong> </strong>= dark brown-black pigment stored in membrane bound granules called <strong><u>melanosomes</u></strong>
-> absorbed by keratinocytes -> melanin <u><strong>protects from UV exposure</strong></u>
Langerhan’s Cells
Macrophages only found in epidermis
-> originate in bone marrow and migrate to skin
-> <strong>phagocytize microbes and stimulate other cells of immune system</strong>
Merkel Cells
Form Merkel disks with sensory nerve ending of epidermal-dermal junction
- <strong>though to aid in touch sensation</strong>
Epidermal Layers
Deepest to Most Superficial
- stratum germinativum (stratum basale)
- stratum spinosum (spiny layer)
- stratum granulosum (granular layer)
- stratum lucidum (clear layer)
- stratum corneum (horny layer)
Stratum germinativum
(stratum basale)
- attached to basement membrane
- new cells produced here and move up
Stratum spinosum
(spiny layer)
- Langerhan’s cells located here
Stratum granulosum
(granular layer)
- keratinization occurs here
Stratum lucidum
(clear layer)
- keratinized clear cells, only in very thick skin areas
Stratum corneum
(horny layer)
- outermost, thickest layer
- cornified remnants of keratinocytes (dandruff)
Keratinization
- produces <u><strong>keratin</strong></u>, a type of surface specialization providing protection and waterproofing for skin’s surface
- as older cells travel up from basal layer, they fill w/ keratoyhyaline and glycolipid granules, lose thier nuclei, cytosol and organelles and become dead sheets of keratin -> dead cells and keratin slough off as dander / dandruff