Ch 6 Genetic Linkage and Mapping - Exam 2! Flashcards

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1
Q

Define a linkage group

A

group of genes that located on the same chromosome

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2
Q

Linkage groups correspond to?

A

the number of haploid chromosomes

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3
Q

When genes A and B are on two different chromosomes, gametes are produced in?

A

equal proportions

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4
Q

When genes A and B are on the same chromosome and are very, very close together, this is known as __ __.

A

complete linkage

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5
Q

When genes A and B are on the same chromosome and are very, very close together, gametes are produced in ?

A

equal proportions

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6
Q

When genes A and B are on the same chromosome not so close, this is known as __ __

A

incomplete linkage

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7
Q

Incomplete linkage produces gametes in?

A

unequal proportions

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8
Q

When genes A and B are on the same chromosome and are very, very far apart, this is known as __ __ ___

A

complete incomplete linkage

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9
Q

Complete incomplete linkage produces gametes in?

A

equal proportions

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10
Q

What do new alleles often change?

A

activity of the cellular product of the gene; phenotype

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11
Q

When genes are in lowercase form they are usually?

A

recessive mutations

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12
Q

When genes are in uppercase form they are usually?

A

dominant mutations

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13
Q

What were Morgan’s two key proposals?

A

crossing over occurs
closer the gametes, the less likely a chiasma forms

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14
Q

Morgan proposed a __ array of genes on a chromosome

A

linear

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15
Q

Recombinant frequency is dependent on?

A

distance between genes

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16
Q

What is the equation for recombinant frequency (RF)?

A

of recombinant offspri5ng/ total # of offspring x 100%

17
Q

What does recominbant frequency provide information on?

A

The physical location of genes on chromosomes

18
Q

yy ww notates?

A

unknown linkage

19
Q

yw/yw notates?

A

loci on the same chromosome

20
Q

y/y w/w notates?

A

loci on different chromosomes

21
Q

Alleles can be __ or __ on the chromosome

A

cis; trans

22
Q

Define crossing over

A

physical exchange between non-sister chromatids of homologus chromosomes

23
Q

Crossing over occurs duing __ __ of ___

A

prophase I; meiosis

24
Q

When are two times crossing over is not detectable?

A
  1. if it occurs outside the two gene markers region
  2. If crossing over occurs and even number of times between the two marker genes
25
Q

T/F: crossing over occurs more randomly along the length of chromosome pairs.

A

True

26
Q

T/F: crossing over involves reciprocal exchange of unequal and corresponding segments

A

FALSE; equal

27
Q

T/F Multiple crosses are not possible in crossing over

A

false

28
Q

What is the purpose of genetic mapping?

A

to determine the gene loci on chromosomes

29
Q

If genes are far, there are __ recombinant offspring

A

many

30
Q

If genes are close, there are __ __ recombinant offspring

A

very few

31
Q

Map distance =

A

of total recombinant offspring / total # of offspring x 100

32
Q

1 map unit (mu) = _ centiMorgans (cM) = _% recombinant frequency

A

1;1

33
Q

What is a test cross?

A

heterozygous crossed with a recessive homozygous to determine an unknown genotype

34
Q

Recombinant offspring __ nonrecombinant offspring

A

<

35
Q

Genetic mapping utilizes a __ cross

A

test