Ch 50 Flashcards
Untreated __ becomes a risk factor for CAD, indicating a need for cardiac stress testing and lipid level monitoring
Hypothyroidism
Results when GH is over secreted after the epiphyses of the long bones have sealed.
Acromegaly
___ disorders usually result from excessive or deficient production and secretion of specific hormones
Pituitary gland
When overseeing of GH occurs before puberty __ results
Gigantism
When secretion of GH during childhood is insufficient __ occurs
Dwarfism
Oversecretion of GH during adulthood results in ___
Acromegaly
An absence of pituitary hormonal activity causes ___ or ___ disease
Panhypopituitarism
Simmonds
Acromegaly results when GH is oversecreted after epiphyses of the long bones have sealed. GH is over produced when the pituitary gland is insensitive to feedback inhibit hormones such as ____, a hypothalamic hormone, and insulin like growth factor (IGF-1)
Somatostatin
___ in combination with a __ is the most reliable method of confirming acromegaly
Glucose tolerance test
GH measurement
Acromegaly
The Tx of choice is ___ (surgical removal of pituitary gland)
Hypophysectomy
Pituitary gland lies within the __, a saddle shaped depression of the __ bone
Sella turcica
Sphenoid
A GH receptor antagonist, is the newest and most effective drug for treating acromegaly. Injected subcut once a day
Pegvisomant
A rare disorder caused by destruction of the pituitary gland followed by cessation of pituitary hormonal activity (complete stop of the pituitary hormone)
Panhypopituitarism (simmonds disease)
The __ and __ atrophy because of the impaired pituitary stimulus, the thyroid and adrenals fail to secreted adequate hormone
Gonads
Genitalia
The __ and __ atrophy because of the impaired pituitary stimulus, the thyroid and adrenals fail to secreted adequate hormone
Gonads
Genitalia