CH 5 Adverse Drug Effects and Drug Interactions Flashcards
Type of drug interaction in which two agents combine to produce a summation response:
Additive effect
An undesirable and potentially harmful action caused by the administration of medication:
Adverse drug effect
A voluntary program that encourages health care providers and consumers to report suspected adverse effects directly to the FDA or the product manufacturer:
FDA Adverse Event Reporting System (FAERS)
By law, reports received by the manufacturers are forwarded to the FDA to be added to the computerized information database.
In some drug inserts, a requirement by the FDA that warns prescribers that the drug carries a risk for serious or fatal adverse effects:
Black box warning
A hyperresponse of body defenses to a particular drug that may result in a diverse range of patient symptoms:
Drug allergies
Occurs when a medication interacts with another substance such as another drug, a dietary supplement, an herbal product, or food that is taken concurrently with the medication, and the drug’s actions are affected:
Drug interaction
Unpredictable and unexplained drug reaction:
Idiosyncratic response
Drug-induced hearing impairment:
Ototoxicity
Determination of whether the risks from a drug outweigh the potential benefits received by taking the medication:
Risk-benefit ratio
Types of drug effects that are less serious than adverse effects, are predictable, and may occur even at therapeutic doses:
Side effects
Type of drug interaction in which two drugs produce an effect that is much greater than would be expected from simply adding the two individual drugs’ responses:
Synergistic effect
Agents that cause birth defects:
Teratogens
