CH 4: Tissue Level Flashcards

1
Q

tissue

A

integrated group of similar cells that usually have a similar embryological origin and are specialized for a specific function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

cell junctions - definition

A

point of contact between adjacent cells - cells can be attached together or to the basement membrane or to the connective tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

cell junctions - functions

A
  1. anchor cells together or to extracellular material (adherens junctions, desmosomes, hemidesmosomes)
  2. form fluid-tight seals between cells (tight junctions)
  3. act as channels that allow ions and molecules to pass from cell to cell (gap junctions)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

CAMs

A

cell adhesion molecules: are transmembrane proteins that bind to each other and to the cytoskeleton

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

adherens junctions - structure

A

transmembrane integral proteins are attached to microfilaments in the cytoskeleton and to the integral membrane proteins of the other cell
made of:
- plaque: dense layer of proteins inside the cell membrane
- cadherins (integral membrane proteins): connect cell to cell
- microfilaments: anchor the cadherin in each cell forming adhesion belts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

adherens junctions - function

A

hold cells together

ex. join epithelial cells together

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

desmosomes - structure

A

similar to adherens junctions, except that cadherins are anchored by intermediate filaments which cross the cytoplasm from one side of the cell to the othere

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

desmosomes - function

A

prevent separation of cells

ex. prevent separation of epidermal cell and cardiac muscle cells under tension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

hemidesmosomes - structure

A

half a desmosome
transmembrane proteins are attached to intermediate filaments + the integrin (anchor protein) links to the protein laminin in the basement membrane

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

basal lamina - structure

A

=basement membrane

  • thin layer of connective tissue underlying eputhelial tissue
  • thin acellular extracellular membrane made of 2 layers:
    • basal lamina: secreted by epithelial cells and composed of collagen fibers, laminin, various glycoproteins and proteoglycans
    • reticular lamina: secreted by connective tissue cells and composed of reticular fibers
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

tight junctions - structure

A

the two plasma membranes are tightly fused together by interlocking membrane proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

tight junctions - function

A

prevent passage of fluids (including water) across a tissue layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

tight junctions - location

A

line GI tract and bladder

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

gap junctions - structure

A

formed by channel proteins called connexins (two connexins=connexon) that span the membrane of two cells
it’s a tiny space between the plasma membranes of two cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

gap junctions - function

A

allow for passage of ions and small molecules between cells, enabling cells to communicate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

gap junctions - location

A

in heart and smooth muscle of the gut

- gap junctions in the heart allow the cardiac muscle cells to beat in sync

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

tissue types

A
  • epithelial
  • muscle
  • connective
  • nervous
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

epithelial tissue - purpose

A
  1. covers and lines surfaces
    - provides selective barriers for movement of material
    ex. barrier btw body and environment (skin, gut)
    ex barrier btw different structures (blood vessels)
    - provides protection from damage/abrasion
    - absorbs nutrients (gut)
  2. forms secretion portions of glands
    - produces mucus, hormones and enzymes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

epithelial tissue - structure

A
  • cells closely packed together (with cell junctions) with intracellular space
  • cells sit on basement membrane
  • consists of apical surface and basal surface
    1. high rate of cell turnover/cell regeneration
    2. has its own good nerve supply
    3. avascular: relies on diffusion from blood blood vessels withing connective tissue from removal of waste and nutrient delivery
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

basement mebrane - function

A

attachment and support for epithelial tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

apical surface

A

“free” surface - epithelial tissue

- region exposed to space inside the organ or lumen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

basal surface

A

adheres to basement mebrane - epithelial tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

basal lamina

A

layer of basement mebrane

  • secreted by epithelial cells
  • composed of collagen fiber, laminin, various glycoproteins and proteoglycans
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

reticular lamina

A

layer of basement membrane

  • secreted by connective tissue
  • composed of reticular fibers
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

epithelial cells - features

A
  • microvilli: increase SA (digestive, urinary and reproductive tracts)
  • cilia: found in portions of the respiratory and reproductive tracts
  • apical surface: region exposed to space inside the organ and lumen
  • basal surface: attaches to underlying epithelial cells or deeper tissues
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

epithelial tissue - classification

A
  • number of cell layers

- shape of cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

epithelial tissue - classification based on number of cell layers

A
  • simple
  • pseudostratified
  • stratified
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

simple (epithelial tissue)

A

have single layer of cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

pseudostratified (epithelial tissue)

A

have single layer but irregular cell shape and nucleus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

stratified (epithelial tissue)

A

have at least two layers of cells

- basal cells replicate by mitosis and replace more superficial layers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

epithelial tissue - function

A

structure determines function

  1. material exchange
    - simple squamous epithelium
  2. secretion and absorption of material
    - simple cuboidal epithelium
    - simple columnar epithelium
  3. protection
    - stratified squamous epithelium
    - pseudostratified ciliated columnar epithelium
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

simple squamous epithelium

A
  • single layer of flat cells
  • thin: adapted for diffusion (lungs, blood, lymph vessels) and filtration (kidneys)
  • specific name in some organs:
    • endhothelium: lines blood vessels
    • endocardium: lines chambers of heart
    • mesothelium: lines serous membranes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

simple squamous epithelium - function

A
  • diffusion (lungs, blood, lymph vessels)

- filtration (kidneys)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

endothelium

A

simple squamous epithelim that lines blood vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

endocardium

A

simple squamous epithelium that lines chambers of the heart

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

mesothelium

A

simple squamous epithelium that lines serous membranes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

stratified squamous epithelium - structure

A

two or more layers of cells
- apical cells are flat
can be keratinized and non-keratinized

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

non-keratinized stratified squamous epithelium - location

A

lines moist surfaces:

  • mouth
  • esophagus
  • part of epiglottis
  • part of pharynx
  • vagina
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

keratin

A

tough, fibrous intracellular protein found in skin, hair and nails

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

keratinized stratified squamous epithelium - location

A

superficial layer of skin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

simple cuboidal epithelium - structure

A

one layer of cube-shaped cells

- nucleus: round and centered

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

simple cuboidal epithelium - function

A

absorption and secretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

simple cuboidal epithelium - location

A

lines kidney tubules, thyroid gland

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

stratified cuboidal epithelium- structure

A

two or more layers of cells

- cells in apical layer are cube-shaped

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

stratified cuboidal epithelium- location

A

in some ducts:

  • sweat glands
  • male urethra
  • esophageal ducts
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

simple columnar epithelium - structure

A

single layer of column-shaped cells

- oval nuclei usually located near the base of cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

simple non-ciliated columnar epithelium - structure

A

contain microvilli at apical surface and goblet cells (secrete mucus)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

goblet cells - function

A

secrete mucus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

simple non-ciliated columnar epithelium - function

A

secretion and absorption

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

simple non-ciliated columnar epithelium - location

A

mucus secretion lubricates:

  • GI
  • respiratory
  • reproductive
  • urinary systems
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
51
Q

simple ciliated columnar epithelium - structure

A

single layer of column-shaped cells with cilia on apical surface
- nucleus: oval, located near the base of the cell
usually contain interspersed goblet cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
52
Q

simple ciliated columnar epithelium - function

A

cilia beat in unison to move fluid, mucus and/or foreign particles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
53
Q

simple ciliated columnar epithelium - location

A

line:

  • bronchioles
  • uterine tubes
  • paranasal sinuses
  • central canal of the spinal cord
  • brain
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
54
Q

pseudostratified columnar epithelium - structure

A
  • single layer of columnar cells
  • appears layered because nuclei are at different levels
  • all cells are attached to the basement membrane
  • not all cells reach the apical layer
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
55
Q

pseudostratified columnar non-ciliated epithelium - structure

A

lacks goblet cells

no cilia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
56
Q

pseudostratified columnar non-ciliated epithelium - location

A

lines epididymis, ducts of larger glands and parts of male urethra

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
57
Q

pseudostratified columnar non-ciliated epithelium - function

A

absorption and secretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
58
Q

pseudostratified ciliated columnar epithelium - structure

A

contain cells with cilia or goblet cells (secrete mucus)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
59
Q

pseudostrlatified ciliated columnar epithelium - location

A

lines airways of upper respiratory tract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
60
Q

pseudostratified ciliated columnar epithelium - function

A

secretion and protection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
61
Q

stratified columnar epithelium - structure

A
  • has at least two layers of cells
  • apical layer has column-shaped cells
  • cells in other layers can be short or irregularly shaped
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
62
Q

stratified columnar epithelium - location

A

lines part of the urethra, esophageal and salivary gland ducts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
63
Q

stratified columnar epithelium - function

A

protection and secretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
64
Q

transitional epithelium - structure

A

variable/transitional appearance

  • relaxed state: looks like stratified cuboidal epithelium but has large and round apical cells
  • stretched state: looks like stratified squamous epithelium as cells flatten
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
65
Q

relaxed state

A

of transitional epithelium: looks like stratified cuboidal epithelium but has large and round apical cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
66
Q

stretched state

A

of transitional epithelium: looks like stratified squamous epithelium as cells flatten

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
67
Q

transitional epithelium - location

A

lines urinary bladder and portions of ureters and urethra

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
68
Q

transitional epithelium - function

A

protection and ability to stretch within

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
69
Q

grandular epithelium

A
  • exocrine glands

- endocrine glands

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
70
Q

exocrine glands - function

A

cells that secrete a product (mucus, sweat, ear wax, saliva, digestive enzymes, …) onto the free surface of the epithelial layer
- connected to surface by ducts (tubes)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
71
Q

exocrine glands - examples

A
  • goblet cells
  • sudoriferous
  • sebaceous
  • salivary glands
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
72
Q

endocrine glands - function

A

secrete hormones into the interstitial fluid followed by diffusion to the bloodstream

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
73
Q

endocrine glands - examples

A
  • pituitary
  • adrenal
  • thyroid gland
74
Q

glands that are both endocrine and exocrine

A
  • pancreas
  • ovaries
  • testes
75
Q

exocrine glands - structure

A
  • has a duct
  • free surface
  • multiple layers
    can be:
  • unicellular - goblet cells
  • multicellular: composed of many cells that form a distinctive microscopic structure or macroscopic organ - sweat glands, sebaceous glands, salivary glands
76
Q

endocrine glands - structure

A
  • thinner layer

- big “blob” of stored hormone

77
Q

unicellular exocrine glands - example

A

goblet cells

78
Q

multicellular exocrine glands - examples

A
  • sweat glands
  • sebaceous glands
  • salivary glands
79
Q

exocrine glands - grandular secretion classification

A
  • merocrine glands
  • apocrine glands
  • holocrine glands
80
Q

exocrine glands - function

A

secretion via exocytosis

81
Q

merocrine glands - function

A
  • mero = part

- discharge secretory product by exocytosis

82
Q

merocrine glands - examples

A
  • salivary glands
  • pancreas glands
  • digestive enzymes
  • sweat glands
83
Q

apocrine glands - function

A
  • apo = away from
  • accumulate secretory product at the apical surface
  • apical surface of the cell pinches off from the cell to form the secretion
  • the remaining part of the cell reapirs itself and the process repeats
84
Q

apocrine glands - examples

A

mammary glands

85
Q

holocrine glands - function

A
  • holo = entire
  • cells accumulate products, die and rupture to release product
  • dead cells are replaced by new ones
86
Q

holocrine glands - examples

A

sebaceous glands

87
Q

connective tissue - characteristics

A
  • made up of cells scattered in ECM
    • cells rarely touch each other due to matrix
    • structure of ECM determines the tissue’s characteristics
  • very abundant and widely distributed
  • good nerve and blood supply except in cartilage and tendons
  • no free surfaces
88
Q

ECM

A

composed of protein fibers and ground substance secreted by connective tissue cells

89
Q

ECM structure determining connective tissue function

A
  • solid, liquid or somewhere in between (gel)

- hard (like bone) or firm and pliable (cartilage)

90
Q

connective tissue cells - origin

A

from mesenchyme

91
Q

mesenchyme - definition

A

embryonic connective tissue composed of mesenchymal cells

92
Q

connective tissue - constituent cells

A
  • blast: immature cells that retain the ability to divide and produce matrix
    • ex. fibroblast, chondroblast, osteoblast
  • cyte: mature cells that cannot divide or produce matrix
    • ex. chondrocyte, osteocyte
93
Q
  • blast
A
  • constituent cells of connective tissue
  • immature cells that retain the ability to divide and produce matrix
    • ex. fibroblast, chondroblast, osteoblast
94
Q
  • cyte
A
  • constituent cells of connective tissue
  • mature cells that cannot divide or produce matrix
    • ex. chondrocyte, osteocyte
95
Q

fibroblasts

A
  • large flat cells

- move through tissue secreting fibers and ground substance

96
Q

macrophages

A
  • develop from monocytes

- engulf microorganisms and cell debris by phagocytosis

97
Q

plasma cells

A
  • develop from B lymphocytes

- produce antibodies that fight against foreign substances

98
Q

neutrophils and eosinophils

A
  • specialized leukocytes
  • not common in normal connective tissue
  • contain toxic molecules and enzymes to fight off invaders
99
Q

neutrophils

A

migrate to sites of bacterial invasion and destroy microbes by phagocytosis

100
Q

eosinophils

A

migrate to sites of parasitic invasion

101
Q

mast cells

A
  • found along blood vessels in connective tissue

- produce histamine that causes dilation of small blood vessels

102
Q

adipocytes

A
  • found subcutaneously and around organs

- fat storage and protection

103
Q

constituent cells of connective tissue - list

A
  1. fibroblasts
  2. macrophages
  3. plasma cells
  4. neutrophils
  5. eosinophils
  6. mast cells
  7. adipocytes
104
Q

ECM - components

A
  1. cells
  2. fibers
  3. ground substance
105
Q

connective tissue - types of fibers

A

all made up of proteins

  1. collagen fibers
  2. reticular fibers
  3. elastic fibers
106
Q

collagen fibers

A
  • made from protein collagen
  • found in most connective tissue
  • often occurs in parallel bundles
  • very strong but flexible
  • ex. bone, cartilage, tendons and ligaments
107
Q

collagen fibers - location

A
  • bone
  • cartilage
  • tendons
  • ligaments
108
Q

reticular fibers

A
  • thin, branched fibers of collagen in fine bundles, with coating of glycoproteins
  • function: provide support for blood vessels and soft organs
    • ex. spleen, lymph nodes
  • form part of the basement membrane
109
Q

reticular fibers - function

A

provide support for blood vessels and soft organs

110
Q

reticular fibers - location

A
  • spleen

- lymph nodes

111
Q

elastic fibers

A
  • smaller diameter fibers made of protein elastin surrounded by glycoprotein fibrillin
  • branch and join to form networks of fibers
  • can stretch up to 150% or relaxed length and then return to its original shape - elasticity
  • ex. lungs, blood vessels, skin
112
Q

elastic fibers - function

A

elasticity: can stretch up to 150% or relaxed length and then return to its original shape

113
Q

elastic fibers - location

A
  • lungs
  • blood vessels
  • skin
114
Q

ground substance

A
  • material between cells and fibers
  • determines consistency of connective tissue
    • can be liquid, semiliquid or calcifies
  • supports cells, holds cells together, stores water, and allows for migration, transport of molecules and chemical reactions
  • contains water and large organic molecules (combinations of proteins and polysaccharides)
115
Q

ground substance - function

A
  • determines consistency of connective tissue
    • can be liquid, semiliquid or calcifies
  • supports cells, holds cells together, stores water, and allows for migration, transport of molecules and chemical reactions
116
Q

classification of connective tissue

A
  • connective tissue proper
    • loose connective tissue
      • areolar
      • adipose
      • reticular
    • dense connective tissue
      • dense regular
      • dense irregular
      • elastic
  • supporting connective tissue
    • cartilage
      • hyaline cartilage
      • fibrous cartilage
      • elastic cartilage
    • bone tissue
      • compact bone
      • spongy bone
  • liquid connective tissue
    • blood
    • lymph plasma
117
Q

classification of proper connective tissue

A
  • loose connective tissue
    - areolar
    - adipose
    - reticular
  • dense connective tissue
    - dense regular
    - dense irregular
    - elastic
118
Q

classification of supporting connective tissue

A
  • cartilage
    - hyaline cartilage
    - fibrous cartilage
    - elastic cartilage
  • bone tissue
    - compact bone
    - spongy bone
119
Q

classification of liquid connective tissue

A
  • blood

- lymph plasma

120
Q

classification of loose connective tissue

A
  • areolar
  • adipose
  • reticular
121
Q

classification of dense connective tissue

A
  • dense regular
  • dense irregular
  • elastic
122
Q

classification of cartilage

A
  • hyaline cartilage
  • fibrous cartilage
  • elastic cartilage
123
Q

classification of bone tissue

A
  • compact bone

- spongy bone

124
Q

broad classification of connective tissue

A
  • connective tissue proper
  • supporting connective tissue
  • liquid connective tissue
125
Q

areolar connective tissue

A
  • most generalized type of conncetive tissue
  • widely distributed: in and around nearly every body structure
    • “packing material” of the body
  • subcutaneous layer of skin, dermis of skin, lamina propria of mucous membranes, around blood vessels, nerves and body organs
  • consists of:
    • fibers: randomly arranged collagen, elastic, reticular
    • cells: fibroblasts, adipocytes, wbc
    • ground substance: gelatinous (semifluid)
      functions: strenght, elasticity, support
126
Q

areolar connective tissue - function

A
  • strength
  • elasticity
  • support
127
Q

loose connective tissue: adipose

A
  • contains adipocytes (derived from fibroblasts)
    • cells specialized for triglyceride storage: stored as one large, centrally located droplet (cytoplasm and nucleus are pushed to the cell periphery)
  • functions: reduces heat loss, energy reserve, supports and protects organs
128
Q

loose connective tissue: adipose - functions

A
  • reduces heat loss
  • energy reserve
  • supports and protects organs
129
Q

loose connective tissue: reticular

A
  • network or reticular fibers and reticular cells
  • forms stroma (framework) of organs
    • ex. liver, spleen, lymph nodes, bone marrow
  • ties cells of smooth muscles together
  • reticular fibers can act as filters
    • ex. in spleen: filters blood to remove worn out red blood cells
    • ex. in lymph nodes: filters the lymph to remove microbes
130
Q

loose connective tissue: reticular - function

A
  • forms stroma (framework) of organs
    • ex. liver, spleen, lymph nodes, bone marrow
  • ties cells of smooth muscles together
  • reticular fibers can act as filters
    • ex. in spleen: filters blood to remove worn out red blood cells
    • ex. in lymph nodes: filters the lymph to remove microbes
131
Q

dense connective tissue

A
  • contains more numerous fibers and fewer cells than loose connective tissue
  • fibers are thicker and denser than in loose connective tissue
  • 3 types: dense regular, dense irregular, elastic
132
Q

dense connective tissue: regular

A
  • collagen fibers regularly arranged in parallel bundles with fibroblast cells in between
    • collagen is not living so tissue does not heal quickly
  • found in tendons and ligaments
  • provides great tensile strength along the fiber axis
    • strong attachment
133
Q

dense connective tissue: regular - function

A
  • provides great tensile strength along the fiber axis

- strong attachment

134
Q

dense connective tissue: irregular

A
  • collagen fibers are irregularly arranged with a few fibroblasts
  • often occurs as sheets such as fasciae (tissue beneath skin and around muscles and organs)
  • tissue can resist tension from any direction
  • makes for very “tough tissues”
    • white of eyeballs, dermis, membranes surrounding the heart, cartilage and bones
135
Q

dense connective tissue: irregular - function

A
  • can resist tension from any direction
  • makes for very “tough tissues”
    • white of eyeballs, dermis, membranes surrounding the heart, cartilage and bones
136
Q

elastic connective tissue

A
  • composed of elastic fibers and fibroblasts
  • can stretch and return to its original shape so it’s very strong
  • found in lung tissue, vocal cords, ligaments between vertebrae and blood vessels
137
Q

elastic connective tissue - function

A

can stretch and return to its original shape so it’s very strong

138
Q

elastic connective tissue - location

A
  • lung tissue
  • vocal cords
  • ligaments between vertebrae
  • blood vessels
139
Q

cartilage

A
  • supporting connective tissue that consists of a dense network of collagen fibes and elastic fibers embedded in chondroitin sulfate (rubbery matrix)
    • collagen fibers make cartilagge strong
    • the chondroitin sulfate makes the cartilage resilient
  • does not have nerves or blood vessels (unlike other connective tissue)
    • secretes anti-angiogenesis factor, which prevents blood vessel growth
  • produced by chondroblasts: mature cartilage contains chondrocytes (cartilage cells)
  • surrounded by a dense irregular connective tissue membrane called the perichondrium
  • 3 types: hyaline, fibrocartilage, elastic
140
Q

hyaline cartilage

A
  • “glassy”
  • most abundant but weakest type of cartilage
  • thin, fine collagen fibers (not visible)
  • abundant chondrocytes in lacunae (small spaces = little lakes) surrounded by perichondrium
  • ground substance is a resilient gel
    • reduces friction and absorbs shock in joints
141
Q

hyaline cartilage - function

A

reduces friction and absorbs shock in joints

142
Q

fibrocartilage

A
  • many more collagen fibers causes rigidity and stiffness
  • chondrocytes scattered among clearly visible, thick bundles of collagen fibers
  • lacks perichondrium
  • strongest type of cartilage
    • intervertebral discs
143
Q

elastic cartilage

A
  • chondrocytes are located within a threadlike matrix of elastic fibers
  • has perichondrium
  • provides shape and elasticity so it maintains shape after deformations
    • found in ear, nose, vocal cartilages, epiglottis
144
Q

elastic cartilage - location

A
  • ear
  • nose
  • vocal cartilage
  • epiglottis
145
Q

bone tissue

A
  • mineralized extracellular matrix
    • calcium and phosphate give hardness
    • interwoven collagen fibers give strength
  • lacunae contain osteocytes (mature bone cells)
  • can be classified as compact or spongy depending on the arrangement of cells and matrix
146
Q

liquid connective tissue

A
  • liquid extracellular matrux
  • two types of liquid connective tissue
    • blood
    • lymph
147
Q

blood

A
  • connective tissue with liquid matrix (ex. blood plasma)
  • cell types include:
    • erythrocytes (rbc)
    • leukocytes (wbc)
    • platelets (cells fragments)
  • found within blood vessels and heart chambers
  • functions: clotting, immune functions, transport O2 and CO2, nutrients and wastes
148
Q

blood - funtions

A
  • clotting
  • immune functions
  • transport O2 and CO2, nutrients and wastes
149
Q

membranes

A
  • are flat sheets of pliable tissue that cover or line a part of the body
  • 2 types: epithelial and synovial
150
Q

epithelial membrane

A
  • consists of epithelial layer and an underlying connective tissue layer
  • 3 types:
    • mucous membranes
    • serous membranes
    • cutaneous membranes
151
Q

types of epithelial membranes

A
  • mucous membranes
  • serous membranes
  • cutaneous membranes
152
Q

synovial membrane

A
  • lines joints

- contains connective tissue but no epithelium

153
Q

mucous membranes

A
  • consist of epithelium over a layer of areolar connective tissue
  • line body cavities that open directly onto the exterior (outside) of the body
    • ex. digestive, reproductive, and most of the urinary tract
  • epithelial layer acts as barriers to microbes
    • connected by tight junctions
  • goblet cells secrete mucus onto the surface, preventing it from drying out
    • also lubricates and traps pathogens
  • epithelium is underlined with areolar connective tissue (lamina propria)
154
Q

mucous membranes - function

A
  • epithelial layer acts as barriers to microbes
    • connected by tight junctions
  • goblet cells secrete mucus onto the surface, preventing it from drying out
    • also lubricates and traps pathogens
155
Q

mucous membranes - location

A
  • digestive
  • reproductive
  • most of urinary tract
156
Q

serous membranes

A
  • lines body cavities that do not open to the exterior
    • abdominal and thoracic cavities
      consist of parietal and visceral layers with serous fluid in between
    • pleura covers lungs, pericardium covers heart, peritoneum covers the visceral organs
    • membrane layers consist of mesothelium (simple squamous epithelium) underlined with areolar connective tissue
157
Q

cutaneous membranes

A
  • covers body surface
  • consists of:
    • epidermis: keratinized stratified squamous epithelium
    • dermis: areolar and irregular dense connective tissue
158
Q

epidermis

A

keratinized stratified squamous epithelium that makes cutaneous membranes

159
Q

dermis

A

areolar and irregular dense connective tissue that makes cutaneous membranes

160
Q

synovial membranes

A
  • line joint cavities of all moveable joints
    • contains connective tissue, but no epithelium (no epithelial cells)
  • discontinuous layer of cells called synoviocytes
    • produce synovial fluid to lubricate joints
161
Q

synoviocytes

A

discontinuous layer of cells that make synovial membranes and produce synovial fluid to lubricate joints

162
Q

muscular tissue

A
  • consists of long cells called muscle fibers
    • each cell contains many contractile proteins composed of actin and myosin
    • use ATP to create force and movement such as motion, posture and heat
163
Q

muscular tissue - function

A

to use ATP to create force and movement such as motion, posture and heat

164
Q

types of muscle tissue

A
  1. skeletal muscle tissue
    • attaches to bones with tendons to promote voluntary movement
  2. cardiac muscle tissue
    • branched, interconnecting at specialized junctions for rapid relay
  3. smooth muscle tissue
    • contracts slowly, involuntary control, found in internal organs
165
Q

skeletal muscle

A
  • consists of long, cylindrical, striated fibers (cells)
    • cells are long and cylindrical with many peripheral nuclei
    • has visible light and dark banding
  • responsible for voluntary contraction/relaxation
  • attached to bones by tendons
  • functions: motion, posture, heat production, protection
166
Q

skeletal muscle - function

A
  • motion
  • posture
  • heat production
  • protection
167
Q

cardiac muscle

A
  • forms most of the walls of the heart and pumps blood to all the parts of the body
  • cells are branched striated cylinders with one central nucleus
  • cells are attached together and communicate with each other by intercalated discs (thickenings of plasma membrane that contain gap junctions and desmosomes)
168
Q

intercalated discs

A

thickenings of plasma membrane that contain gap junctions and desmosomes

169
Q

cardiac muscle - function

A

form wall of heart and pump blood to all parts of the body

170
Q

smooth muscle

A
  • spindle-shaped cell with a single central nucleus
    • lack striations (smooth)
    • cells are often connected by gap junctions to quickly send messeges back and forth
  • found in walls of hollow organs (blood vessels, GI tract, bladder, …)
  • involuntary contraction/relaxation
171
Q

smooth muscle - location

A

walls of hollow organs

  • blood vessels
  • GI tract
  • bladder
172
Q

smooth muscle - function

A

responsible for involuntary contraction/relaxation

173
Q

nervous tissue

A

two cell types:

  1. neurons: function cells of nervous system that conduct electrical impulses and are made of:
    • dendrites: receive info and conduct signals toward the cell body
    • cell body: contains nucleus
    • axons: conduct signals away from the cell body
  2. neuroglial cells: supportive cells
    • insulate axons for faster conduction, nourish and regulare neuronal function
174
Q

neurons

A

function cells of nervous system that conduct electrical impulses and are made of:

  • dendrites: receives info and conduct signals towards the cell body
  • cell body: contains nucleus
  • axons: conduct signals away from the cell body
175
Q

neuroglial cells

A

supportive cells

- insulate axons for faster conduction, nourish and regulate neuronal function

176
Q

dendrites

A

receives info and conduct signals towards the cell body in neurons

177
Q

cell body

A

contains nucleus in the neuron

178
Q

axons

A

conduct signals away from the cell body in neurons

179
Q

nervous tissue - functions

A
  • senses stimuli and converts them into action potential (nerve impulses)
  • conducts nerve impulses to other neurons, muscle fibers or glands
  • responsible for maintaning homeostasis and for everything we do
180
Q

nervous tissue - location

A
  • CNS: brain and spinal cord

- PNS: nerves containing sensory and motor neurons

181
Q

CNS

A

brain and spinal cord

182
Q

PNS

A

nerves containing sensory and motor neurons