Ch 4, 5 tissue repair Flashcards
regeneration
damaged tissue replaced by same kind of tissue
fibrosis
tissue replaced by fibrous connective tissue =scar tissue
steps in tissue repair; inflammation
a. cardinal signs
Redness, Heat, Swelling, Pain, immobilization
b, steps in inflammatory response
1. inflammatory chemicals released by damaged cells
-dilation of blood cells-increases the blood flow area (redness and heat)
-chemicals trigger pain receptors (pain)
2. Capillaries become leaky
-exudate leaks out of capillaries into injured areas
-swelling and pain=immobilizes the area
3. exudate contains WBC, fluid and plasma proteins
-proteins facilitate healing
-WBCs attack invaders
4. clotting occurs, scab forms
step 2; organization and restored blood supply
- clot replaced by granulation tissue
- capillaries grow in from near by - epithelium regenerates
- fibroblasts produce collagen fiber
- debris phagocytized
step 3; regeneration and fibrosis
- scab detaches
- fibrous tissue matures, epithelium thickens, takes on mature characteristics
- results in fully regenerated epithelium with underlying scar tissue
epithelium regeneration
very well, bone, areolar, irregular dense and blood
nervous tissue and cardiac muscle regeneration
poorly
vitamin C
lack of vitamin c prevents tissue healing, needed for collagen synthesis